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    lapA lipopolysaccharide assembly protein A [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944936, updated on 2-May-2024

    Summary

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    Gene symbol
    lapA
    Gene description
    lipopolysaccharide assembly protein A
    Primary source
    ASAP:ABE-0004298
    Locus tag
    b1279
    See related
    ECOCYC:G6637
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1274; yciS
    Summary
    YciS is predicted to have two TM segments; the first segment may be erroneously predicted to be a type II signal peptide prediction. [More information is available at EcoGene: EG13904]. YciS is an inner membrane protein with two predicted transmembrane domains. [More information is available at EcoCyc: G6637].
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    Genomic context

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    Sequence:
    NC_000913.3 (1340243..1340551)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene GTP cyclohydrolase 2 Neighboring gene phosphatidylglycerophosphatase B Neighboring gene lipopolysaccharide assembly protein B Neighboring gene orotidine-5'-phosphate decarboxylase Neighboring gene putative translation factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inner Membrane Protein YhcB Interacts with RodZ Involved in Cell Shape Maintenance in Escherichia coli. Li G, et al. ISRN Mol Biol, 2012. PMID 27335665, Free PMC Article
    2. The global transcriptional response of Escherichia coli to induced sigma 32 protein involves sigma 32 regulon activation followed by inactivation and degradation of sigma 32 in vivo. Zhao K, et al. J Biol Chem, 2005 May 6. PMID 15757896
    3. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Nonaka G, et al. Genes Dev, 2006 Jul 1. PMID 16818608, Free PMC Article
    4. Cell-free complements in vivo expression of the E. coli membrane proteome. Savage DF, et al. Protein Sci, 2007 May. PMID 17456747, Free PMC Article
    5. ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis. Mehla J, et al. J Biol Chem, 2021 Jan-Jun. PMID 33895137, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipopolysaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    lipopolysaccharide assembly protein A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1340243..1340551
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415795.1 lipopolysaccharide assembly protein A [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415795.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A895NZT8
      Conserved Domains (1) summary
      COG3771
      Location:1 → 101
      YciS; Uncharacterized membrane protein YciS, DUF1049 family [Function unknown]
    Nucleotide Protein
    Heading Accession and Version

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