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    kch K(+) channel Kch [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945841, updated on 2-May-2024

    Summary

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    Gene symbol
    kch
    Gene description
    K(+) channel Kch
    Primary source
    ASAP:ABE-0004189
    Locus tag
    b1250
    See related
    ECOCYC:EG11606
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1244
    Summary
    Consistently co-purifies with the degradosome. [More information is available at EcoGene: EG11606]. Kch is a member of the Voltage-gated Ion Channel (VIC) Superfamily of transporters . [More information is available at EcoCyc: EG11606].
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    Genomic context

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    Sequence:
    NC_000913.3 (1309016..1310269, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cardiolipin synthase A Neighboring gene uncharacterized protein YciY Neighboring gene protein YciI Neighboring gene Ton complex subunit TonB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography. Kuang Q, et al. Structure, 2015 Jan 6. PMID 25497729
    2. Assembly of Kch, a putative potassium channel from Escherichia coli. Lundbäck AK, et al. J Struct Biol, 2009 Nov. PMID 19631752
    3. Gain-of-function mutations indicate that Escherichia coli Kch forms a functional K+ conduit in vivo. Kuo MM, et al. EMBO J, 2003 Aug 15. PMID 12912904, Free PMC Article
    4. Functional properties of Kch, a prokaryotic homologue of eukaryotic potassium channels. Munsey TS, et al. Biochem Biophys Res Commun, 2002 Sep 13. PMID 12220501
    5. Analysis of a putative voltage-gated prokaryotic potassium channel. Ungar D, et al. Eur J Biochem, 2001 Oct. PMID 11606201

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The structure of Kch, a channel of this type from Escherichia coli, in a lipid environment using electron crystallography.
      Title: Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography.
    Submit: New GeneRIF Correction

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within potassium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    K(+) channel Kch

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1309016..1310269 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415766.1 K(+) channel Kch [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415766.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7R7N5
      Conserved Domains (1) summary
      PRK10537
      Location:3 → 402
      PRK10537; voltage-gated potassium channel protein
    Nucleotide Protein
    Heading Accession and Version

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