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    CG17562 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42021, updated on 10-May-2024

    Summary

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    Official Symbol
    CG17562provided by FlyBase
    Primary source
    FLYBASE:FBgn0038449
    Locus tag
    Dmel_CG17562
    See related
    AllianceGenome:FB:FBgn0038449
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17562
    Summary
    Predicted to enable fatty-acyl-CoA reductase (alcohol-forming) activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to be active in peroxisome. Is expressed in adult fat body; adult head; and embryonic/larval oenocyte. Orthologous to human FAR1 (fatty acyl-CoA reductase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG17562 in Genome Data Viewer
    Location:
    89D5-89D5; 3-59 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16615309..16617154)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12441031..12442876)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene neuropeptide F Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-2494 stem loop Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural variation at a single gene generates sexual antagonism across fitness components in Drosophila. Rusuwa BB, et al. Curr Biol, 2022 Jul 25. PMID 35700732
    2. Neural clocks and Neuropeptide F/Y regulate circadian gene expression in a peripheral metabolic tissue. Erion R, et al. Elife, 2016 Apr 14. PMID 27077948, Free PMC Article
    3. Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. Chiang YN, et al. PLoS Genet, 2016 Jun. PMID 27333054, Free PMC Article
    4. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
    5. Fat Quality Impacts the Effect of a High-Fat Diet on the Fatty Acid Profile, Life History Traits and Gene Expression in Drosophila melanogaster. Eickelberg V, et al. Cells, 2022 Dec 14. PMID 36552807, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in long-chain fatty-acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17562-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16615309..16617154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142309.2 → NP_650566.1  uncharacterized protein Dmel_CG17562 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650566.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VES7
      Related
      FBpp0082779
      Conserved Domains (3) summary
      cd09071
      Location:362 → 452
      FAR_C; C-terminal domain of fatty acyl CoA reductases
      cd05236
      Location:12 → 329
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      PLN02996
      Location:10 → 442
      PLN02996; fatty acyl-CoA reductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VES7 Q9VES7

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