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    Ir31a Ionotropic receptor 31a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318912, updated on 10-May-2024

    Summary

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    Official Symbol
    Ir31aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 31aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051718
    Locus tag
    Dmel_CG31718
    See related
    AllianceGenome:FB:FBgn0051718
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    31a; CG31718; DmelIR31a; Dmel\CG31718; IR31a
    Summary
    Predicted to enable ligand-gated ion channel activity. Involved in detection of chemical stimulus involved in sensory perception. Predicted to be integral component of membrane. Is expressed in adult olfactory receptor neuron Ir31a; antennal coeloconic sensillum ac1; and antennal lobe glomerulus VL2p. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

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    See Ir31a in Genome Data Viewer
    Location:
    31E1-31E1; 2-42 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10405565..10408197)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10405565..10408197)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Malate dehydrogenase 1 Neighboring gene CCR4-NOT transcription complex subunit 4 Neighboring gene uncharacterized protein Neighboring gene Like Sm protein 4 Neighboring gene Ribosomal protein S27A Neighboring gene Intronic Protein 259 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Olfactory receptor pseudo-pseudogenes. Prieto-Godino LL, et al. Nature, 2016 Nov 3. PMID 27776356, Free PMC Article
    2. Evaluation of the DREAM Technique for a High-Throughput Deorphanization of Chemosensory Receptors in Drosophila. Koerte S, et al. Front Mol Neurosci, 2018. PMID 30356801, Free PMC Article
    3. An ammonium transporter is a non-canonical olfactory receptor for ammonia. Vulpe A, et al. Curr Biol, 2021 Aug 9. PMID 34111404, Free PMC Article
    4. Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants. Arguello JR, et al. Elife, 2021 Mar 5. PMID 33666172, Free PMC Article
    5. Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines. Hussain A, et al. PLoS Biol, 2016 May. PMID 27145030, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 31a
    Names
    CG31718-PC
    CG31718-PD
    Ir31a-PC
    Ir31a-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10405565..10408197
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164926.2 → NP_723585.2  ionotropic receptor 31a, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723585.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IPB8
      Conserved Domains (1) summary
      pfam00060
      Location:401 → 622
      Lig_chan; Ligand-gated ion channel

    2. NM_001273417.1 → NP_001260346.1  ionotropic receptor 31a, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260346.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCT4
      Conserved Domains (1) summary
      pfam00060
      Location:401 → 624
      Lig_chan; Ligand-gated ion channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PCT4 M9PCT4
    Q8IPB8 Q8IPB8

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