GLP1R glucagon like peptide 1 receptor [Gallus gallus (chicken)] - Gene

Summary

Symbol: GLP1Rprovided by CGNC
Full Name: glucagon like peptide 1 receptorprovided by CGNC
Primary source: CGNC:7660
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: GLP-1R
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (28981897..29061242, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (28909400..28988745, complement)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The 5'-flanking region of cGLP1R gene displays promoter activities in cultured HepG2 and HEK293 cells, suggesting that it may control cGLP1R gene transcription in chicken tissues, including nonpancreatic tissues.
Title: Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants.
GLP-1 receptor genes were highly expressed in the gastrointestinal tract, brain, pancreas and abdominal fat
Title: Expression of proglucagon and proglucagon-derived peptide hormone receptor genes in the chicken.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables glucagon receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables peptide hormone binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: glucagon-like peptide 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135551.1 → NP_001129023.1 glucagon-like peptide 1 receptor precursor

See identical proteins and their annotated locations for NP_001129023.1

Status: PROVISIONAL

Source sequence(s)

EU770586

UniProtKB/TrEMBL

B4ZY91, F1N8H7

Conserved Domains (2) summary

pfam00002
Location:137 → 394

7tm_2; 7 transmembrane receptor (Secretin family)

pfam02793
Location:60 → 127

HRM; Hormone receptor domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

28981897..29061242 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

28909400..28988745 complement

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GenBank, FASTA, Sequence Viewer (Graphics)