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    Cyb561d1 cytochrome b-561 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 72023, updated on 28-May-2024

    Summary

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    Official Symbol
    Cyb561d1provided by MGI
    Official Full Name
    cytochrome b-561 domain containing 1provided by MGI
    Primary source
    MGI:MGI:1919273
    See related
    Ensembl:ENSMUSG00000048796 AllianceGenome:MGI:1919273
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1600010M23Rik
    Summary
    Predicted to enable heme binding activity and oxidoreductase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human CYB561D1 (cytochrome b561 family member D1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thymus adult (RPKM 5.4), spleen adult (RPKM 4.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Cyb561d1 in Genome Data Viewer
    Location:
    3 F2.3; 3 46.86 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108103082..108109542, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108195771..108202226, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40122 Neighboring gene adhesion molecule with Ig like domain 1 Neighboring gene ataxin 7-like 2 Neighboring gene synaptophysin like 2 Neighboring gene SIVA1, apoptosis-inducing factor pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane ascorbate ferrireductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane monodehydroascorbate reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable transmembrane reductase CYB561D1
    Names
    cytochrome b561 domain-containing protein 1
    NP_001074789.2
    NP_082337.1
    XP_006502189.1
    XP_006502190.1
    XP_006502191.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081320.2 → NP_001074789.2  probable transmembrane reductase CYB561D1 isoform 1

      See identical proteins and their annotated locations for NP_001074789.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BB853561, BC060107
      Consensus CDS
      CCDS38598.1
      UniProtKB/Swiss-Prot
      A2AE42, B2RPT5
      Related
      ENSMUSP00000102266.2, ENSMUST00000106655.2
      Conserved Domains (1) summary
      cd08761
      Location:32 → 212
      Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

    2. NM_028061.1 → NP_082337.1  probable transmembrane reductase CYB561D1 isoform 2

      See identical proteins and their annotated locations for NP_082337.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation from a downstream ATG and an isoform (2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK164441, BC060107
      Consensus CDS
      CCDS38599.1
      UniProtKB/TrEMBL
      Q3TPE5, Q6PAS2
      Related
      ENSMUSP00000070361.7, ENSMUST00000065664.7
      Conserved Domains (1) summary
      cd08761
      Location:1 → 154
      Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      108103082..108109542 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502127.3 → XP_006502190.1  probable transmembrane reductase CYB561D1 isoform X2

      UniProtKB/TrEMBL
      Q6PAS2
      Conserved Domains (1) summary
      cd08761
      Location:6 → 155
      Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

    2. XM_006502128.4 → XP_006502191.1  probable transmembrane reductase CYB561D1 isoform X3

      See identical proteins and their annotated locations for XP_006502191.1

      UniProtKB/TrEMBL
      Q3TPE5, Q6PAS2
      Related
      ENSMUST00000155099.2
      Conserved Domains (1) summary
      cd08761
      Location:1 → 154
      Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product

    3. XM_006502126.2 → XP_006502189.1  probable transmembrane reductase CYB561D1 isoform X1

      UniProtKB/TrEMBL
      Q6PAS2
      Conserved Domains (1) summary
      cd08761
      Location:2 → 164
      Cyt_b561_CYB561D2_like; Eukaryotic cytochrome b(561), including the CYB561D2 gene product
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2AE42.1 GenPept UniProtKB/Swiss-Prot:A2AE42

    Gene LinkOut

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