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    Gal3st1 galactose-3-O-sulfotransferase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 683713, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Gal3st1provided by RGD
    Official Full Name
    galactose-3-O-sulfotransferase 1provided by RGD
    Primary source
    RGD:1583379
    See related
    Ensembl:ENSRNOG00000042041 AllianceGenome:RGD:1583379
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable galactosylceramide sulfotransferase activity. Predicted to be involved in galactosylceramide biosynthetic process; glycerolipid metabolic process; and myelination. Predicted to act upstream of or within spermatogenesis. Predicted to be integral component of membrane. Orthologous to human GAL3ST1 (galactose-3-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 23.9), Brain (RPKM 19.5) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gal3st1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (83094265..83109992)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (78868049..78886402)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (84231473..84247371)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene transcobalamin 2 Neighboring gene pescadillo ribosomal biogenesis factor 1 Neighboring gene SEC14-like lipid binding 4 Neighboring gene uncharacterized LOC103693135 Neighboring gene uncharacterized LOC120096646

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. cDNA cloning, genomic cloning, and tissue-specific regulation of mouse cerebroside sulfotransferase. Hirahara Y, et al. Eur J Biochem, 2000 Apr. PMID 10727929
    2. Paranodal junction formation and spermatogenesis require sulfoglycolipids. Honke K, et al. Proc Natl Acad Sci U S A, 2002 Apr 2. PMID 11917099, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables galactosylceramide sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactosylceramide sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in galactosylceramide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within galactosylceramide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in galactosylceramide metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in glycerolipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in myelination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within myelination ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sphingolipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    galactosylceramide sulfotransferase
    NP_001102917.1
    XP_006251444.1
    XP_006251445.1
    XP_063129696.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109447.1 → NP_001102917.1  galactosylceramide sulfotransferase

      See identical proteins and their annotated locations for NP_001102917.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473963
      UniProtKB/TrEMBL
      A6IKE0, D3ZCT9
      Related
      ENSRNOP00000062589.2, ENSRNOT00000066362.3
      Conserved Domains (1) summary
      cl22970
      Location:31 → 440
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      83094265..83109992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251382.5 → XP_006251444.1  galactosylceramide sulfotransferase isoform X2

      See identical proteins and their annotated locations for XP_006251444.1

      UniProtKB/TrEMBL
      Q5PQK7
      Conserved Domains (1) summary
      cl22970
      Location:4 → 408
      Sulfotransfer_2; Sulfotransferase family

    2. XM_063273626.1 → XP_063129696.1  galactosylceramide sulfotransferase isoform X1

    3. XM_006251383.5 → XP_006251445.1  galactosylceramide sulfotransferase isoform X2

      See identical proteins and their annotated locations for XP_006251445.1

      UniProtKB/TrEMBL
      Q5PQK7
      Conserved Domains (1) summary
      cl22970
      Location:4 → 408
      Sulfotransfer_2; Sulfotransferase family
    Nucleotide Protein Strain
    Heading Accession and Version

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