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    CG5800 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32742, updated on 10-May-2024

    Summary

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    Official Symbol
    CG5800provided by FlyBase
    Primary source
    FLYBASE:FBgn0030855
    Locus tag
    Dmel_CG5800
    See related
    AllianceGenome:FB:FBgn0030855
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg5800; Dmel\CG5800; DmRH14
    Summary
    Predicted to enable RNA helicase activity. Involved in larval somatic muscle development. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval lymph gland; embryonic/larval muscle system; foregut primordium; gastrula embryo; and germ layer derivative. Orthologous to human DDX10 (DEAD-box helicase 10). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG5800 in Genome Data Viewer
    Location:
    16B10-16B10; 1-57 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17636281..17639003)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17530314..17533036)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 24 kDa subunit Neighboring gene uncharacterized protein Neighboring gene Rho GTPase activating protein p190 Neighboring gene Integrator 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rapid and efficient generation of GFP-knocked-in Drosophila by the CRISPR-Cas9-mediated genome editing. Kina H, et al. Dev Growth Differ, 2019 May. PMID 31037730
    2. Evolution of intron/exon structure of DEAD helicase family genes in Arabidopsis, Caenorhabditis, and Drosophila. Boudet N, et al. Genome Res, 2001 Dec. PMID 11731501, Free PMC Article
    3. RNA silencing in the antiviral innate immune defence--role of DEAD-box RNA helicases. Ulvila J, et al. Scand J Immunol, 2010 Mar. PMID 20415780
    4. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article
    5. New negative feedback regulators of Egfr signaling in Drosophila. Butchar JP, et al. Genetics, 2012 Aug. PMID 22595244, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in larval somatic muscle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5800-PA
    NP_573230.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17636281..17639003
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133002.2 → NP_573230.1  uncharacterized protein Dmel_CG5800 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573230.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VX34
      Related
      FBpp0074227
      Conserved Domains (4) summary
      PRK01297
      Location:2 → 471
      PRK01297; ATP-dependent RNA helicase RhlB; Provisional
      cd00079
      Location:311 → 437
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:74 → 277
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam13959
      Location:474 → 530
      DUF4217; Domain of unknown function (DUF4217)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VX34 Q9VX34

    Gene LinkOut

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