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    Nxpe2 neurexophilin and PC-esterase domain family, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100363350, updated on 31-Mar-2024

    Summary

    Official Symbol
    Nxpe2provided by RGD
    Official Full Name
    neurexophilin and PC-esterase domain family, member 2provided by RGD
    Primary source
    RGD:2323193
    See related
    Ensembl:ENSRNOG00000027847 AllianceGenome:RGD:2323193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. Orthologous to human NXPE2 (neurexophilin and PC-esterase domain family member 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 22.0), Testes (RPKM 19.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nxpe2 in Genome Data Viewer
    Location:
    8q23
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (57558250..57596039, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (48661708..48695555, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (60333201..60359944, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094370 Neighboring gene uncharacterized LOC134480045 Neighboring gene neurexophilin and PC-esterase domain family member 4 Neighboring gene neurexophilin and PC-esterase domain family, member 1 Neighboring gene RNA exonuclease 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    NXPE family member 2; neurexophilin and PC-esterase domain family, member 2
    Names
    rCG58102-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428898.1NP_001415827.1  neurexophilin and PC-esterase domain family, member 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      57558250..57596039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082357.2XP_038938285.1  NXPE family member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZLD6, A6J489
      Related
      ENSRNOP00000078638.1
      Conserved Domains (1) summary
      pfam06312
      Location:114243
      Neurexophilin
    2. XM_002729901.6XP_002729947.2  NXPE family member 2 isoform X1

      See identical proteins and their annotated locations for XP_002729947.2

      UniProtKB/TrEMBL
      A6J489
      Conserved Domains (1) summary
      pfam06312
      Location:139268
      Neurexophilin; Neurexophilin

    RNA

    1. XR_010054377.1 RNA Sequence

    2. XR_010054376.1 RNA Sequence