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    Minar2 membrane integral NOTCH2 associated receptor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291580, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Minar2provided by RGD
    Official Full Name
    membrane integral NOTCH2 associated receptor 2provided by RGD
    Primary source
    RGD:1312005
    See related
    Ensembl:ENSRNOG00000022429 AllianceGenome:RGD:1312005
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1312005
    Summary
    Predicted to be integral component of membrane. Orthologous to human MINAR2 (membrane integral NOTCH2 associated receptor 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 59.2), Uterus (RPKM 7.1) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Minar2 in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (54737670..54752388)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (52539714..52554465)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (54108471..54123061)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene N(alpha)-acetyltransferase 50, NatE catalytic subunit, pseudogene 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 19 Neighboring gene uncharacterized LOC120098155 Neighboring gene uncharacterized LOC134483036 Neighboring gene chondroitin sulfate synthase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cholesterol binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in angiogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within exploration behavior ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within homeostasis of number of cells within a tissue ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within locomotory behavior ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within sensory perception of sound ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within walking behavior ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in stereocilium ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    major intrinsically disordered NOTCH2-binding receptor 1-like
    Names
    UPF0258 protein KIAA1024-like homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106144.2 → NP_001099614.2  major intrinsically disordered NOTCH2-binding receptor 1-like

      See identical proteins and their annotated locations for NP_001099614.2

      Status: VALIDATED

      Source sequence(s)
      BC166445
      UniProtKB/TrEMBL
      A6IX95, B2GUX6, F7EQ04
      Related
      ENSRNOP00000029403.5, ENSRNOT00000029239.7
      Conserved Domains (1) summary
      pfam06789
      Location:52 → 186
      UPF0258; uncharacterized protein family (UPF0258)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      54737670..54752388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096695.2 → XP_038952623.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X5

    2. XM_063277211.1 → XP_063133281.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X7

    3. XM_039096688.2 → XP_038952616.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X3

    4. XM_039096696.2 → XP_038952624.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X6

    5. XM_063277209.1 → XP_063133279.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X1

      UniProtKB/TrEMBL
      B2GUX6

    6. XM_006254754.4 → XP_006254816.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X2

      UniProtKB/TrEMBL
      B2GUX6
      Conserved Domains (1) summary
      pfam06789
      Location:71 → 203
      UPF0258; uncharacterized protein family (UPF0258)

    7. XM_039096689.2 → XP_038952617.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X4

      UniProtKB/TrEMBL
      A0A0G2JZK9, A6IX97
      Conserved Domains (1) summary
      pfam06789
      Location:42 → 144
      UPF0258; Uncharacterized protein family (UPF0258)

    8. XM_063277210.1 → XP_063133280.1  major intrinsically disordered NOTCH2-binding receptor 1-like isoform X4

      UniProtKB/TrEMBL
      A0A0G2JZK9, A6IX97
    Nucleotide Protein Strain
    Heading Accession and Version

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