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    Gpn3 GPN-loop GTPase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360810, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Gpn3provided by RGD
    Official Full Name
    GPN-loop GTPase 3provided by RGD
    Primary source
    RGD:1303034
    See related
    Ensembl:ENSRNOG00000001278 AllianceGenome:RGD:1303034
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Atpbd1c
    Summary
    Predicted to enable GTPase activity. Predicted to be part of protein-containing complex. Orthologous to human GPN3 (GPN-loop GTPase 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 92.9), Kidney (RPKM 88.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gpn3 in Genome Data Viewer
    Location:
    12q16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (39850070..39859032, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (34189285..34198251, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (39670746..39679364, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352447 Neighboring gene actin related protein 2/3 complex, subunit 3 Neighboring gene small nucleolar RNA SNORA67 Neighboring gene family with sequence similarity 216, member A Neighboring gene VPS29 retromer complex component Neighboring gene RAD9 checkpoint clamp component B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    GPN-loop GTPase 3
    Names
    ATP-binding domain 1 family member C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001393837.1 → NP_001380766.1  GPN-loop GTPase 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      Q6R518
      Conserved Domains (1) summary
      cd17872
      Location:1 → 227
      GPN3; GPN-loop GTPase 3

    2. NM_201991.2 → NP_973720.2  GPN-loop GTPase 3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/Swiss-Prot
      Q6R518
      UniProtKB/TrEMBL
      A6J199, G3V652
      Related
      ENSRNOP00000001722.4, ENSRNOT00000001722.6
      Conserved Domains (1) summary
      cd17872
      Location:4 → 249
      GPN3; GPN-loop GTPase 3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      39850070..39859032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063271534.1 → XP_063127604.1  GPN-loop GTPase 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6R518
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6R518.1 GenPept UniProtKB/Swiss-Prot:Q6R518

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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