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    galla-2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39221, updated on 10-May-2024

    Summary

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    Official Symbol
    galla-2provided by FlyBase
    Primary source
    FLYBASE:FBgn0036107
    Locus tag
    Dmel_CG7949
    See related
    AllianceGenome:FB:FBgn0036107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7949; CIAO2B; Dmel\CG7949; Galla-2; galla2; Galla2
    Summary
    Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of CIA complex. Is expressed in larval imaginal tissue. Orthologous to human CIAO2B (cytosolic iron-sulfur assembly component 2B). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See galla-2 in Genome Data Viewer
    Location:
    67F1-67F1; 3-33 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10882890..10883573)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10875990..10876673)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Biogenesis of lysosome-related organelles complex 1, subunit 4 Neighboring gene uncharacterized protein Neighboring gene OXA1L mitochondrial inner membrane protein Neighboring gene Cuticular protein 67Fa1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crumbs interacts with Xpd for nuclear division control in Drosophila. Yeom E, et al. Oncogene, 2015 May 21. PMID 25065591
    2. Structural insights into Fe-S protein biogenesis by the CIA targeting complex. Kassube SA, et al. Nat Struct Mol Biol, 2020 Aug. PMID 32632277
    3. Ciao1 interacts with Crumbs and Xpd to regulate organ growth in Drosophila. Jung J, et al. Cell Death Dis, 2020 May 13. PMID 32404863, Free PMC Article
    4. Mms19 is a mitotic gene that permits Cdk7 to be fully active as a Cdk-activating kinase. Nag RN, et al. Development, 2018 Jan 25. PMID 29361561, Free PMC Article
    5. Crumbs, Galla and Xpd are required for Kinesin-5 regulation in mitosis and organ growth in Drosophila. Hwang JH, et al. J Cell Sci, 2020 Jun 23. PMID 32501288

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein maturation by [4Fe-4S] cluster transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein maturation by iron-sulfur cluster transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of CIA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    galla-2
    Names
    CG7949-PA
    galla-2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      10882890..10883573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140159.2 → NP_648416.1  galla-2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648416.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VTC4
      UniProtKB/TrEMBL
      A0A1B2AL76, Q29QJ3
      Related
      FBpp0075999
      Conserved Domains (1) summary
      cl00941
      Location:1 → 154
      DUF59; Domain of unknown function DUF59
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTC4.1 Q9VTC4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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