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    mRpL10 mitochondrial ribosomal protein L10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33182, updated on 10-May-2024

    Summary

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    Official Symbol
    mRpL10provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L10provided by FlyBase
    Primary source
    FLYBASE:FBgn0031231
    Locus tag
    Dmel_CG11488
    See related
    AllianceGenome:FB:FBgn0031231
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11488; Dmel\CG11488; L10; RpL10
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in adult head; adult heart; embryonic/larval midgut; and organism. Orthologous to human MRPL10 (mitochondrial ribosomal protein L10). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See mRpL10 in Genome Data Viewer
    Location:
    21B4-21B4; 2-0.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (203779..204782)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (203779..204782)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene split ends Neighboring gene TBC1 domain family member 15/17 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44220 Neighboring gene kismet

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function. Li HB, et al. DNA Cell Biol, 2016 Nov. PMID 27726420, Free PMC Article
    2. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Hoskins RA, et al. Genome Res, 2011 Feb. PMID 21177961, Free PMC Article
    3. DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. Killip LE, et al. Dev Biol, 2012 Nov 15. PMID 22960233
    4. Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation. Grobler Y, et al. PLoS Pathog, 2018 Nov. PMID 30422992, Free PMC Article
    5. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein L10
    Names
    CG11488-PA
    mRpL10-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      203779..204782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078716.3 → NP_523440.1  mitochondrial ribosomal protein L10 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523440.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VPL3
      Related
      FBpp0077783
      Conserved Domains (1) summary
      cd05797
      Location:74 → 227
      Ribosomal_L10; Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPL3.1 Q9VPL3

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