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    Mtcl3 MTCL family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 67412, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mtcl3provided by MGI
    Official Full Name
    MTCL family member 3provided by MGI
    Primary source
    MGI:MGI:1914662
    See related
    Ensembl:ENSMUSG00000038916 AllianceGenome:MGI:1914662
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Soga3; 6330407J23Rik
    Summary
    Predicted to be involved in regulation of autophagy. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Orthologous to human SOGA3 (SOGA family member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in whole brain E14.5 (RPKM 19.0), CNS E18 (RPKM 16.3) and 5 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mtcl3 in Genome Data Viewer
    Location:
    10 A4; 10 16.52 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (29019992..29075626)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (29143996..29199630)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene UPF0762 protein C6orf58 homolog Neighboring gene phosphatidylethanolamine-binding protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_26173 Neighboring gene STARR-seq mESC enhancer starr_26174 Neighboring gene RIKEN cDNA 9330159F19 gene Neighboring gene STARR-seq mESC enhancer starr_26176 Neighboring gene predicted gene, 46218 Neighboring gene STARR-seq mESC enhancer starr_26177 Neighboring gene enoyl Coenzyme A hydratase domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E6827 Neighboring gene ring finger protein 146 Neighboring gene predicted gene, 25596

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    microtubule cross-linking factor 3
    Names
    SOGA family member 3
    protein SOGA3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026138.2NP_080414.2  microtubule cross-linking factor 3 precursor

      See identical proteins and their annotated locations for NP_080414.2

      Status: VALIDATED

      Source sequence(s)
      AC153912, AK018139, AK030682, CD355864
      Consensus CDS
      CCDS35875.1
      UniProtKB/Swiss-Prot
      Q6NZL0, Q8BLM2, Q9CSN3, Q9CU45
      Related
      ENSMUSP00000090293.3, ENSMUST00000092629.4
      Conserved Domains (2) summary
      pfam00261
      Location:357569
      Tropomyosin; Tropomyosin
      pfam11365
      Location:519613
      DUF3166; Protein of unknown function (DUF3166)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      29019992..29075626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)