Cox20 cytochrome c oxidase assembly factor COX20 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cox20provided by RGD
Official Full Name: cytochrome c oxidase assembly factor COX20provided by RGD
Primary source: RGD:1309105
See related: AllianceGenome:RGD:1309105
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam36a; RGD1309105
Summary: Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX20 (cytochrome c oxidase assembly factor COX20). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 500.8), Thymus (RPKM 406.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q25

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (92592260..92604129)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (90065900..90075386)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (96219853..96224023)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129823 (e-PCR)
- UniSTS:213111

RH131715 (e-PCR)
- UniSTS:214998

RH132995 (e-PCR)
- UniSTS:216278

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mitochondrial cytochrome c oxidase assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial cytochrome c oxidase assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial cytochrome c oxidase assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cytochrome c oxidase assembly factor COX20

Names: COX20 Cox2 chaperone homolog; COX20 cytochrome C oxidase assembly factor; family with sequence similarity 36, member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001105976.1 → NP_001099446.1 cytochrome c oxidase assembly factor COX20

See identical proteins and their annotated locations for NP_001099446.1

Status: PROVISIONAL

Source sequence(s)

CH473985

UniProtKB/TrEMBL

A0A8I5ZSY5, A6JGE3

Conserved Domains (1) summary

pfam12597
Location:13 → 97

DUF3767; Protein of unknown function (DUF3767)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086031.1 Reference GRCr8

Range

92592260..92604129

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039090533.2 → XP_038946461.1 cytochrome c oxidase assembly factor COX20 isoform X1

Conserved Domains (1) summary

pfam12597
Location:13 → 76

DUF3767; Protein of unknown function (DUF3767)