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    Ssbp2 single-stranded DNA binding protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361877, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Ssbp2provided by RGD
    Official Full Name
    single-stranded DNA binding protein 2provided by RGD
    Primary source
    RGD:1562968
    See related
    Ensembl:ENSRNOG00000016213 AllianceGenome:RGD:1562968
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562968
    Summary
    Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 158.2), Heart (RPKM 65.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ssbp2 in Genome Data Viewer
    Location:
    2q12
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (24385494..24673768)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22650488..22938669)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (20416795..20707838)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485571 Neighboring gene uncharacterized LOC134485570 Neighboring gene uncharacterized LOC120100665 Neighboring gene uncharacterized LOC103691419 Neighboring gene transfer RNA leucine (anticodon AAG) 15 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene acyl-CoA thioesterase 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    single-stranded DNA-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399027.1 → NP_001385956.1  single-stranded DNA-binding protein 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:99 → 355
      SSDP; Single-stranded DNA binding protein, SSDP

    2. NM_001399028.1 → NP_001385957.1  single-stranded DNA-binding protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6ALH6
      Related
      ENSRNOP00000094798.1, ENSRNOT00000109181.1
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83 → 346
      SSDP; Single-stranded DNA binding protein, SSDP

    3. NM_001399029.1 → NP_001385958.1  single-stranded DNA-binding protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83 → 339
      SSDP; Single-stranded DNA binding protein, SSDP

    4. NM_001399030.1 → NP_001385959.1  single-stranded DNA-binding protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83 → 338
      SSDP; Single-stranded DNA binding protein, SSDP

    5. NM_001399031.1 → NP_001385960.1  single-stranded DNA-binding protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    6. NM_001399032.1 → NP_001385961.1  single-stranded DNA-binding protein 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:92 → 309
      SSDP; Single-stranded DNA binding protein, SSDP

    7. NM_001399033.1 → NP_001385962.1  single-stranded DNA-binding protein 2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:92 → 308
      SSDP; Single-stranded DNA binding protein, SSDP

    8. NM_001399034.1 → NP_001385963.1  single-stranded DNA-binding protein 2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6GBJ4
      Related
      ENSRNOP00000084174.1, ENSRNOT00000113453.1

    9. NM_001399035.1 → NP_001385964.1  single-stranded DNA-binding protein 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      Related
      ENSRNOP00000090009.1, ENSRNOT00000095831.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      24385494..24673768
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282020.1 → XP_063138090.1  single-stranded DNA-binding protein 2 isoform X33

    2. XM_063282022.1 → XP_063138092.1  single-stranded DNA-binding protein 2 isoform X34

      UniProtKB/TrEMBL
      A6I4P6

    3. XM_039103448.2 → XP_038959376.1  single-stranded DNA-binding protein 2 isoform X31

      Conserved Domains (1) summary
      pfam04503
      Location:19 → 272
      SSDP; Single-stranded DNA binding protein, SSDP

    4. XM_063282003.1 → XP_063138073.1  single-stranded DNA-binding protein 2 isoform X2

    5. XM_039103427.2 → XP_038959355.1  single-stranded DNA-binding protein 2 isoform X3

      Conserved Domains (2) summary
      smart00667
      Location:80 → 108
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:162 → 425
      SSDP; Single-stranded DNA binding protein, SSDP

    6. XM_039103428.2 → XP_038959356.1  single-stranded DNA-binding protein 2 isoform X4

      Conserved Domains (2) summary
      smart00667
      Location:80 → 108
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:162 → 418
      SSDP; Single-stranded DNA binding protein, SSDP

    7. XM_039103429.2 → XP_038959357.1  single-stranded DNA-binding protein 2 isoform X5

      Conserved Domains (2) summary
      smart00667
      Location:80 → 108
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:162 → 417
      SSDP; Single-stranded DNA binding protein, SSDP

    8. XM_063282006.1 → XP_063138076.1  single-stranded DNA-binding protein 2 isoform X10

    9. XM_063282007.1 → XP_063138077.1  single-stranded DNA-binding protein 2 isoform X11

    10. XM_039103430.2 → XP_038959358.1  single-stranded DNA-binding protein 2 isoform X12

      Conserved Domains (2) summary
      smart00667
      Location:80 → 108
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:171 → 388
      SSDP; Single-stranded DNA binding protein, SSDP

    11. XM_063282008.1 → XP_063138078.1  single-stranded DNA-binding protein 2 isoform X13

    12. XM_008760646.4 → XP_008758868.2  single-stranded DNA-binding protein 2 isoform X6

    13. XM_063282004.1 → XP_063138074.1  single-stranded DNA-binding protein 2 isoform X7

    14. XM_008760648.4 → XP_008758870.2  single-stranded DNA-binding protein 2 isoform X8

      UniProtKB/TrEMBL
      F1M3J3

    15. XM_008760649.4 → XP_008758871.2  single-stranded DNA-binding protein 2 isoform X9

      UniProtKB/TrEMBL
      F1M3J3

    16. XM_063282009.1 → XP_063138079.1  single-stranded DNA-binding protein 2 isoform X14

    17. XM_063282010.1 → XP_063138080.1  single-stranded DNA-binding protein 2 isoform X16

    18. XM_063282011.1 → XP_063138081.1  single-stranded DNA-binding protein 2 isoform X17

    19. XM_008760653.4 → XP_008758875.2  single-stranded DNA-binding protein 2 isoform X18

    20. XM_039103432.2 → XP_038959360.1  single-stranded DNA-binding protein 2 isoform X15

      UniProtKB/TrEMBL
      F1M3J3
      Conserved Domains (1) summary
      pfam04503
      Location:116 → 380
      SSDP; Single-stranded DNA binding protein, SSDP

    21. XM_039103433.2 → XP_038959361.1  single-stranded DNA-binding protein 2 isoform X19

      UniProtKB/TrEMBL
      F1M3J3
      Related
      ENSRNOP00000021857.7
      Conserved Domains (1) summary
      pfam04503
      Location:105 → 369
      SSDP; Single-stranded DNA binding protein, SSDP

    22. XM_039103434.2 → XP_038959362.1  single-stranded DNA-binding protein 2 isoform X21

      UniProtKB/TrEMBL
      A0A8I6AA81
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:99 → 363
      SSDP; Single-stranded DNA binding protein, SSDP

    23. XM_039103447.2 → XP_038959375.1  single-stranded DNA-binding protein 2 isoform X31

      Conserved Domains (1) summary
      pfam04503
      Location:19 → 272
      SSDP; Single-stranded DNA binding protein, SSDP

    24. XM_063282015.1 → XP_063138085.1  single-stranded DNA-binding protein 2 isoform X25

    25. XM_063282016.1 → XP_063138086.1  single-stranded DNA-binding protein 2 isoform X27

    26. XM_039103436.2 → XP_038959364.1  single-stranded DNA-binding protein 2 isoform X22

      UniProtKB/TrEMBL
      A0A8I6AA81
      Related
      ENSRNOP00000089419.1
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:83 → 347
      SSDP; Single-stranded DNA binding protein, SSDP

    27. XM_039103442.2 → XP_038959370.1  single-stranded DNA-binding protein 2 isoform X28

      UniProtKB/TrEMBL
      A0A8I6AA81, A0A8I6AH80
      Related
      ENSRNOP00000094192.1
      Conserved Domains (2) summary
      smart00667
      Location:19 → 45
      LisH; Lissencephaly type-1-like homology motif
      pfam04503
      Location:92 → 316
      SSDP; Single-stranded DNA binding protein, SSDP

    28. XM_063282012.1 → XP_063138082.1  single-stranded DNA-binding protein 2 isoform X20

    29. XM_063282017.1 → XP_063138087.1  single-stranded DNA-binding protein 2 isoform X29

    30. XM_063282014.1 → XP_063138084.1  single-stranded DNA-binding protein 2 isoform X24

    31. XM_063282013.1 → XP_063138083.1  single-stranded DNA-binding protein 2 isoform X23

    32. XM_063282019.1 → XP_063138089.1  single-stranded DNA-binding protein 2 isoform X32

    33. XM_063282021.1 → XP_063138091.1  single-stranded DNA-binding protein 2 isoform X34

      UniProtKB/TrEMBL
      A6I4P6

    34. XM_063282024.1 → XP_063138094.1  single-stranded DNA-binding protein 2 isoform X35

      UniProtKB/TrEMBL
      A6I4P7

    35. XM_063282002.1 → XP_063138072.1  single-stranded DNA-binding protein 2 isoform X1

    36. XM_063282018.1 → XP_063138088.1  single-stranded DNA-binding protein 2 isoform X31

    37. XM_039103440.2 → XP_038959368.1  single-stranded DNA-binding protein 2 isoform X26

      UniProtKB/TrEMBL
      F1M3J3
      Conserved Domains (1) summary
      pfam04503
      Location:56 → 320
      SSDP; Single-stranded DNA binding protein, SSDP

    38. XM_039103445.2 → XP_038959373.1  single-stranded DNA-binding protein 2 isoform X30

      UniProtKB/TrEMBL
      F1M3J3
      Conserved Domains (1) summary
      pfam04503
      Location:40 → 304
      SSDP; Single-stranded DNA binding protein, SSDP

    39. XM_039103449.2 → XP_038959377.1  single-stranded DNA-binding protein 2 isoform X31

      Conserved Domains (1) summary
      pfam04503
      Location:19 → 272
      SSDP; Single-stranded DNA binding protein, SSDP

    40. XM_063282023.1 → XP_063138093.1  single-stranded DNA-binding protein 2 isoform X34

      UniProtKB/TrEMBL
      A6I4P6

    41. XM_063282025.1 → XP_063138095.1  single-stranded DNA-binding protein 2 isoform X35

      UniProtKB/TrEMBL
      A6I4P7
    Nucleotide Protein Strain
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