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    Cdcp2 CUB domain containing protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 242603, updated on 12-May-2024

    Summary

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    Official Symbol
    Cdcp2provided by MGI
    Official Full Name
    CUB domain containing protein 2provided by MGI
    Primary source
    MGI:MGI:3045328
    See related
    Ensembl:ENSMUSG00000047636 AllianceGenome:MGI:3045328
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D030010E02Rik
    Summary
    Predicted to be located in extracellular region. Orthologous to human CDCP2 (CUB domain containing protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Cdcp2 in Genome Data Viewer
    Location:
    4 C7; 4 50.02 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (106954088..106971420)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107096891..107114223)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene single-stranded DNA binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_11016 Neighboring gene STARR-seq mESC enhancer starr_11017 Neighboring gene STARR-positive B cell enhancer ABC_E3500 Neighboring gene VISTA enhancer mm1261 Neighboring gene STARR-positive B cell enhancer ABC_E1035 Neighboring gene mitochondrial ribosomal protein L37 Neighboring gene cytochrome b5 reductase-like Neighboring gene predicted gene 12802 Neighboring gene transcription elongation factor A (SII) N-terminal and central domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E4641 Neighboring gene transmembrane protein 59

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CUB domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172873.3 → NP_766461.1  CUB domain-containing protein 2 precursor

      See identical proteins and their annotated locations for NP_766461.1

      Status: PROVISIONAL

      Source sequence(s)
      AK050720
      Consensus CDS
      CCDS18430.1
      UniProtKB/Swiss-Prot
      Q8BQH6
      Related
      ENSMUSP00000061401.3, ENSMUST00000062495.3
      Conserved Domains (2) summary
      cd00041
      Location:145 → 254
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam00431
      Location:30 → 140
      CUB; CUB domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      106954088..106971420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253566.1 → XP_030109426.1  CUB domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1Y7VJ18
      Related
      ENSMUSP00000152236.2, ENSMUST00000221740.2
      Conserved Domains (1) summary
      pfam00431
      Location:30 → 140
      CUB; CUB domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BQH6.1 GenPept UniProtKB/Swiss-Prot:Q8BQH6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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