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    Ns5atp4 NS5A transactivated protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361985, updated on 13-Apr-2024

    Summary

    Official Symbol
    Ns5atp4provided by RGD
    Official Full Name
    NS5A transactivated protein 4provided by RGD
    Primary source
    RGD:1359625
    See related
    Ensembl:ENSRNOG00000017758 AllianceGenome:RGD:1359625
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in phagocytosis. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in Golgi apparatus and mitochondrion. Orthologous to human C1orf43 (chromosome 1 open reading frame 43). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 463.7), Muscle (RPKM 427.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ns5atp4 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (177792070..177804943)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (175494406..175507281)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189400696..189413614)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691621 Neighboring gene HCLS1 associated protein X-1 Neighboring gene ubiquitin associated protein 2-like Neighboring gene cilia and flagella associated protein 141 Neighboring gene microRNA 190b Neighboring gene tropomyosin 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112629, MGC124898

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phagocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phagocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    protein C1orf43 homolog
    Names
    NS5A (hepatitis C virus) transactivated protein 4 like 1
    NS5A transactivated protein 4 like 1
    uncharacterized protein C1orf43 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014174.3NP_001014196.1  protein C1orf43 homolog isoform 2

      See identical proteins and their annotated locations for NP_001014196.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q5XII8
      UniProtKB/TrEMBL
      A6J6J2
      Related
      ENSRNOP00000046713.3, ENSRNOT00000046919.6
      Conserved Domains (1) summary
      pfam07406
      Location:6170
      NICE-3; NICE-3 protein
    2. NM_001413650.1NP_001400579.1  protein C1orf43 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I6GL14, A6J6J1, Q4KMA3
      Related
      ENSRNOP00000095163.1, ENSRNOT00000100523.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      177792070..177804943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)