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    Or49a Odorant receptor 49a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36350, updated on 10-May-2024

    Summary

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    Official Symbol
    Or49aprovided by FlyBase
    Official Full Name
    Odorant receptor 49aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033727
    Locus tag
    Dmel_CG13158
    See related
    AllianceGenome:FB:FBgn0033727
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    49a; 49A.1; CG13158; Dmel\CG13158; DmOr49a; DOR10; OR49a
    Summary
    Predicted to enable odorant binding activity and olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell and olfactory behavior. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in larval head segment and olfactory system. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

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    See Or49a in Genome Data Viewer
    Location:
    49A2-49A2; 2-67 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12393483..12394842)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8280988..8282347)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 49Ac Neighboring gene Cuticular protein 49Ad Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 49Ae

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Avoids Parasitoids by Sensing Their Semiochemicals via a Dedicated Olfactory Circuit. Ebrahim SA, et al. PLoS Biol, 2015 Dec. PMID 26674493, Free PMC Article
    2. Olfactory coding: connecting odorant receptor expression and behavior in the Drosophila larva. Stocker RF. Curr Biol, 2006 Jan 10. PMID 16401410
    3. Neuropeptide F signaling regulates parasitoid-specific germline development and egg-laying in Drosophila. Sadanandappa MK, et al. PLoS Genet, 2021 Mar. PMID 33770070, Free PMC Article
    4. Chemical Cues that Guide Female Reproduction in Drosophila melanogaster. Billeter JC, et al. J Chem Ecol, 2018 Sep. PMID 29557077, Free PMC Article
    5. Combinatorial Codes and Labeled Lines: How Insects Use Olfactory Cues to Find and Judge Food, Mates, and Oviposition Sites in Complex Environments. Haverkamp A, et al. Front Physiol, 2018. PMID 29449815, Free PMC Article

    See all (69) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in olfactory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of smell NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 49a
    Names
    CG13158-PA
    Or49a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12393483..12394842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078987.3 → NP_523711.3  odorant receptor 49a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523711.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V6A9
      Related
      FBpp0087029, FBtr0087918
      Conserved Domains (1) summary
      pfam02949
      Location:88 → 384
      7tm_6; 7tm Odorant receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V6A9.3 Q9V6A9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
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