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    CG33061 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318838, updated on 10-May-2024

    Summary

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    Official Symbol
    CG33061provided by FlyBase
    Primary source
    FLYBASE:FBgn0053061
    Locus tag
    Dmel_CG33061
    See related
    AllianceGenome:FB:FBgn0053061
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13057; Dmel\CG33061
    Summary
    Predicted to enable cation channel activity. Predicted to be located in membrane. Is expressed in eye. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 14. Orthologous to human TMEM38A (transmembrane protein 38A) and TMEM38B (transmembrane protein 38B). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG33061 in Genome Data Viewer
    Location:
    72E1-72E1; 3-44 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16329795..16331227)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16322895..16324327)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene retinin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. Xu H, et al. EMBO J, 2004 Feb 25. PMID 14963491, Free PMC Article
    2. Drosophila auditory organ genes and genetic hearing defects. Senthilan PR, et al. Cell, 2012 Aug 31. PMID 22939627
    3. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    4. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
    5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in sarcoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33061-PB
    CG33061-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16329795..16331227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275008.1 → NP_001261937.1  uncharacterized protein Dmel_CG33061, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261937.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PFQ0
      Conserved Domains (1) summary
      pfam05197
      Location:45 → 95
      TRIC; TRIC channel

    2. NM_001104150.3 → NP_001097620.1  uncharacterized protein Dmel_CG33061, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097620.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86BI6
      Conserved Domains (1) summary
      pfam05197
      Location:45 → 231
      TRIC; TRIC channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PFQ0 M9PFQ0
    Q86BI6 Q86BI6

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