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    CG12479 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50344, updated on 10-May-2024

    Summary

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    Official Symbol
    CG12479provided by FlyBase
    Primary source
    FLYBASE:FBgn0040871
    Locus tag
    Dmel_CG12479
    See related
    AllianceGenome:FB:FBgn0040871
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12479; Minos1a
    Summary
    Predicted to be part of MICOS complex. Predicted to be active in mitochondrion. Orthologous to human MICOS10 (mitochondrial contact site and cristae organizing system subunit 10). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG12479 in Genome Data Viewer
    Location:
    12E2-12E2; 1-48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14151579..14152006, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14045612..14046039, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Serine-AGA 2-2 Neighboring gene long non-coding RNA:CR44658 Neighboring gene Nascent-associated complex beta-subunit-like, testis 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Li S, et al. Cell Rep, 2020 Aug 4. PMID 32755582, Free PMC Article
    2. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article
    3. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of MICOS complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12479-PA
    mitochondrial INner membrane organizing system 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14151579..14152006 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144227.2 → NP_652484.1  uncharacterized protein Dmel_CG12479 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652484.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VY65
      Related
      FBpp0073691
      Conserved Domains (1) summary
      pfam04418
      Location:3 → 66
      DUF543; Domain of unknown function (DUF543)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VY65 Q9VY65

    Gene LinkOut

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