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    Cog8 component of oligomeric golgi complex 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291990, updated on 5-Mar-2024

    Summary

    Official Symbol
    Cog8provided by RGD
    Official Full Name
    component of oligomeric golgi complex 8provided by RGD
    Primary source
    RGD:1307074
    See related
    Ensembl:ENSRNOG00000020379 AllianceGenome:RGD:1307074
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIh. Orthologous to human COG8 (component of oligomeric golgi complex 8). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 114.0), Adrenal (RPKM 102.8) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cog8 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (51861376..51872126, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (34951625..34962377, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (39246656..39257406, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 4 homolog A Neighboring gene uncharacterized LOC134483350 Neighboring gene peptide deformylase (mitochondrial) Neighboring gene nucleolar pre-rRNA processing protein NIP7 Neighboring gene transmembrane p24 trafficking protein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, vesicle recycling within Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Golgi transport complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106182.2NP_001099652.1  conserved oligomeric Golgi complex subunit 8

      See identical proteins and their annotated locations for NP_001099652.1

      Status: VALIDATED

      Source sequence(s)
      BC098009, CO395229
      UniProtKB/TrEMBL
      A6IYY7, A6IYY8, B5DF86
      Related
      ENSRNOP00000063394.1, ENSRNOT00000066312.3
      Conserved Domains (1) summary
      pfam04124
      Location:56394
      Dor1; Dor1-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      51861376..51872126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)