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    Cand7 Lung seven transmembrane receptor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831970, updated on 15-Oct-2023

    Summary

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    Gene symbol
    Cand7
    Gene description
    Lung seven transmembrane receptor family protein
    Primary source
    Araport:AT5G18520
    Locus tag
    AT5G18520
    See related
    TAIR:AT5G18520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    candidate G-protein Coupled Receptor 7; T28N17.5
    Summary
    Encodes a candidate G-protein Coupled Receptor that is involved in the regulation of root growth by bacterial N-acyl-homoserine lactones (AHLs) and plays a role in mediating interactions between plants and microbes.
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    Genomic context

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    See Cand7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (6144855..6146603)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene vacuolar sorting-associated protein (DUF946) Neighboring gene Protein kinase superfamily protein Neighboring gene Aminotransferase-like, plant mobile domain family protein Neighboring gene protein serine/threonine kinase Neighboring gene E3 ubiquitin-protein ligase Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A G protein-coupled receptor-like module regulates cellulose synthase secretion from the endomembrane system in Arabidopsis. McFarlane HE, et al. Dev Cell, 2021 May 17. PMID 33878345, Free PMC Article
    2. Two G-protein-coupled-receptor candidates, Cand2 and Cand7, are involved in Arabidopsis root growth mediated by the bacterial quorum-sensing signals N-acyl-homoserine lactones. Jin G, et al. Biochem Biophys Res Commun, 2012 Jan 20. PMID 22206669
    3. Whole proteome identification of plant candidate G-protein coupled receptors in Arabidopsis, rice, and poplar: computational prediction and in-vivo protein coupling. Gookin TE, et al. Genome Biol, 2008. PMID 18671868, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results suggest that Cand2 and Cand7 are involved in the regulation of root growth by bacterial N-acyl-homoserine lactones and that GPCRs play a role in mediating interactions between plants and microbes. [Cand7]
      Title: Two G-protein-coupled-receptor candidates, Cand2 and Cand7, are involved in Arabidopsis root growth mediated by the bacterial quorum-sensing signals N-acyl-homoserine lactones.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    • At5g18520_Arabidopsis_lyrata_ssp._lyrata_CAN10 (e-PCR)
    • At5g18520_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)

    Homology

    NM_121857.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in G protein-coupled receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of cellulose biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to molecule of bacterial origin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to molecule of bacterial origin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    is_active_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Lung seven transmembrane receptor family protein
    NP_197353.1
    • Lung seven transmembrane receptor family protein; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Transmembrane receptor, eukaryota (InterPro:IPR009637); BEST Arabidopsis thaliana protein match is: Lung seven transmembrane receptor family protein (TAIR:AT3G09570.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6144855..6146603
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121857.4 → NP_197353.1  Lung seven transmembrane receptor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197353.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JY11, Q56YB8, Q681D1
      UniProtKB/TrEMBL
      A0A178UFK2, A0A5S9Y596, A0A654G2C2
      Conserved Domains (1) summary
      cl21735
      Location:135 → 416
      Lung_7-TM_R; Lung seven transmembrane receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JY11.1

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