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    Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499300, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ptprcapprovided by RGD
    Official Full Name
    protein tyrosine phosphatase, receptor type, C-associated proteinprovided by RGD
    Primary source
    RGD:1559601
    See related
    Ensembl:ENSRNOG00000021724 AllianceGenome:RGD:1559601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human PTPRCAP (protein tyrosine phosphatase receptor type C associated protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 1424.1), Spleen (RPKM 764.6) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ptprcap in Genome Data Viewer
    Location:
    1q43
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210878593..210880752)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (201449133..201451293)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219403970..219406129)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene calcium binding protein 4 Neighboring gene ribosomal protein L35A, pseudogene 6 Neighboring gene coronin 1B Neighboring gene ribosomal protein S6 kinase B2 Neighboring gene carnosine synthase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. Kirchgessner H, et al. J Exp Med, 2001 Jun 4. PMID 11390434, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein tyrosine phosphatase receptor type C-associated protein
    Names
    protein tyrosine phosphatase, receptor type, C polypeptide-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024289.1 → NP_001019460.1  protein tyrosine phosphatase receptor type C-associated protein precursor

      See identical proteins and their annotated locations for NP_001019460.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088279
      UniProtKB/TrEMBL
      F7FP40, Q5I0I6
      Related
      ENSRNOP00000038539.3, ENSRNOT00000029607.4
      Conserved Domains (1) summary
      pfam15713
      Location:58 → 197
      PTPRCAP; Protein tyrosine phosphatase receptor type C-associated

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      210878593..210880752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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