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    Fnbp4 formin binding protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311183, updated on 30-Mar-2024

    Summary

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    Official Symbol
    Fnbp4provided by RGD
    Official Full Name
    formin binding protein 4provided by RGD
    Primary source
    RGD:1309238
    See related
    Ensembl:ENSRNOG00000007241 AllianceGenome:RGD:1309238
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in nuclear speck. Orthologous to human FNBP4 (formin binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 258.4), Spleen (RPKM 211.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fnbp4 in Genome Data Viewer
    Location:
    3q24
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (97188852..97218916)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (76733012..76763077)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (79570610..79610122)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 160 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene ribosomal protein S26, pseudogene 9 Neighboring gene AGBL carboxypeptidase 2 Neighboring gene mitochondrial carrier 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC105867

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    formin-binding protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013159.3 → NP_001013177.3  formin-binding protein 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HN70
      Related
      ENSRNOP00000009687.7, ENSRNOT00000009687.7
      Conserved Domains (2) summary
      cd00201
      Location:604 → 635
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:222 → 249
      WW; WW domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      97188852..97218916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104892.2 → XP_038960820.1  formin-binding protein 4 isoform X1

      Conserved Domains (2) summary
      cd00201
      Location:631 → 662
      WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
      pfam00397
      Location:249 → 276
      WW; WW domain

    2. XM_063283657.1 → XP_063139727.1  formin-binding protein 4 isoform X2

    3. XM_039104893.2 → XP_038960821.1  formin-binding protein 4 isoform X3

      Conserved Domains (1) summary
      pfam00397
      Location:249 → 276
      WW; WW domain

    RNA

    1. XR_005501861.2 RNA Sequence

    2. XR_005501862.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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