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    Synj1 synaptojanin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 85238, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Synj1provided by RGD
    Official Full Name
    synaptojanin 1provided by RGD
    Primary source
    RGD:69434
    See related
    Ensembl:ENSRNOG00000002051 AllianceGenome:RGD:69434
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables phosphatase activity; protein C-terminus binding activity; and protein domain specific binding activity. Involved in several processes, including nervous system development; positive regulation of receptor-mediated endocytosis; and response to retinoic acid. Located in cytoplasm; neuron projection; and synaptic membrane. Part of clathrin coat of coated pit. Is active in parallel fiber to Purkinje cell synapse and presynapse. Colocalizes with microtubule. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 20; and developmental and epileptic encephalopathy 53. Orthologous to human SYNJ1 (synaptojanin 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 382.5), Spleen (RPKM 139.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Synj1 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (43678709..43755526, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (30192629..30269447, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31105784..31181573, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene cilia and flagella associated protein 298 Neighboring gene PAX3 and PAX7 binding protein 1 Neighboring gene exosomal polycystin 1 interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins. Adayev T, et al. Biochem Biophys Res Commun, 2006 Dec 29. PMID 17097615, Free PMC Article
    2. Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues. Woscholski R. Methods Enzymol, 2002. PMID 11665617
    3. Identification and characterisation of a novel splice variant of synaptojanin1. Woscholski R, et al. FEBS Lett, 1998 Jul 31. PMID 9710239
    4. Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties. Ramjaun AR, et al. J Biol Chem, 1996 Oct 4. PMID 8798761
    5. A presynaptic inositol-5-phosphatase. McPherson PS, et al. Nature, 1996 Jan 25. PMID 8552192

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. concentrated in presynaptic nerve terminals, where it dephosphorylates a pool of phosphatidylinositol
      Title: Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses.
    2. EphrinB-EphB signalling regulates clathrin-mediated endocytosis in various cellular contexts by influencing protein interactions and phosphoinositide turnover through tyrosine phosphorylation of synaptojanin 1.
      Title: EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1.
    3. characterization and purification from rat brain
      Title: Characterization and purification of phosphatidylinositol trisphosphate 5-phosphatase from rat brain tissues.
    4. Two proteins with prominent functions in endocytosis, synaptojanin-1 and dynamin, bind to the SH3 domain of human Myo1E.
      Title: Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables EH domain binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SH3 domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables SH3 domain binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables SH3 domain binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables inositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,4,5-trisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol phosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol phosphate 5-phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3-phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3-phosphate phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4-phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-4-phosphate phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in learning IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within learning ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in learning ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within neurotransmitter transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in phosphatidylinositol dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphatidylinositol dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in phosphatidylinositol dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within phosphatidylinositol metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of endosome organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of endosome organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of gliogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of receptor-mediated endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in postsynaptic neurotransmitter receptor internalization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of postsynaptic neurotransmitter receptor internalization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to cytokine IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to retinoic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic vesicle endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic vesicle endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within synaptic vesicle endocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in synaptic vesicle endocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in synaptic vesicle endocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within synaptic vesicle priming ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within synaptic vesicle transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within synaptic vesicle uncoating ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in synaptic vesicle uncoating ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of clathrin coat of coated pit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of membrane coat ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in parallel fiber to Purkinje cell synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in perinuclear region of cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in presynapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in presynapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in presynapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in synaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in terminal bouton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in vesicle membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    synaptojanin-1
    Names
    synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1
    NP_001401979.1
    NP_445928.3
    XP_038944618.1
    XP_038944619.1
    XP_038944620.1
    XP_038944621.1
    XP_038944622.1
    XP_038944623.1
    XP_038944624.1
    XP_038944625.1
    XP_038944627.1
    XP_038944628.1
    XP_038944630.1
    XP_038944634.1
    XP_063126875.1
    XP_063126876.1
    XP_063126877.1
    XP_063126879.1
    XP_063126880.1
    XP_063126881.1
    XP_063126882.1
    XP_063126883.1
    XP_063126884.1
    XP_063126885.1
    XP_063126886.1
    XP_063126887.1
    XP_063126888.1
    XP_063126889.1
    XP_063126890.1
    XP_063126891.1
    XP_063126892.1
    XP_063126893.1
    XP_063126894.1
    XP_063126895.1
    XP_063126896.1
    XP_063126897.1
    XP_063126898.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001415050.1 → NP_001401979.1  synaptojanin-1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      D4ABN3
      Related
      ENSRNOP00000045019.6, ENSRNOT00000052033.7

    2. NM_053476.4 → NP_445928.3  synaptojanin-1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6JLD7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      43678709..43755526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270813.1 → XP_063126883.1  synaptojanin-1 isoform X16

      UniProtKB/TrEMBL
      A0A8I6AHP8

    2. XM_063270805.1 → XP_063126875.1  synaptojanin-1 isoform X4

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8

    3. XM_063270811.1 → XP_063126881.1  synaptojanin-1 isoform X13

      UniProtKB/TrEMBL
      A0A8I6AHP8

    4. XM_063270806.1 → XP_063126876.1  synaptojanin-1 isoform X6

      UniProtKB/TrEMBL
      A0A8I6AFG5

    5. XM_063270807.1 → XP_063126877.1  synaptojanin-1 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AFG5

    6. XM_039088691.2 → XP_038944619.1  synaptojanin-1 isoform X2

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8
      UniProtKB/TrEMBL
      A0A8L2QTB1
      Related
      ENSRNOP00000060346.4
      Conserved Domains (4) summary
      cd09098
      Location:573 → 908
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:1094 → 1495
      PHA03247; large tegument protein UL36; Provisional
      COG5329
      Location:100 → 520
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      cl17169
      Location:907 → 1049
      RRM_SF; RNA recognition motif (RRM) superfamily

    7. XM_039088697.2 → XP_038944625.1  synaptojanin-1 isoform X15

      UniProtKB/TrEMBL
      A0A8I6AHP8
      Conserved Domains (4) summary
      cd09098
      Location:568 → 903
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam03154
      Location:1023 → 1448
      Atrophin-1; Atrophin-1 family
      cl17169
      Location:902 → 1044
      RRM_SF; RNA recognition motif (RRM) superfamily

    8. XM_063270809.1 → XP_063126879.1  synaptojanin-1 isoform X10

      UniProtKB/TrEMBL
      A6JLD5

    9. XM_039088692.2 → XP_038944620.1  synaptojanin-1 isoform X3

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8
      Conserved Domains (4) summary
      cd09098
      Location:568 → 903
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:1089 → 1490
      PHA03247; large tegument protein UL36; Provisional
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      cl17169
      Location:902 → 1044
      RRM_SF; RNA recognition motif (RRM) superfamily

    10. XM_039088696.2 → XP_038944624.1  synaptojanin-1 isoform X12

      UniProtKB/TrEMBL
      A0A8I6AHP8
      Related
      ENSRNOP00000092530.1
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam03154
      Location:1031 → 1456
      Atrophin-1; Atrophin-1 family
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    11. XM_039088695.2 → XP_038944623.1  synaptojanin-1 isoform X9

      UniProtKB/TrEMBL
      A0A8I6AFG5
      Related
      ENSRNOP00000086242.1
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      pfam03154
      Location:1031 → 1469
      Atrophin-1; Atrophin-1 family
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    12. XM_039088693.2 → XP_038944621.1  synaptojanin-1 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AFG5
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:1073 → 1304
      PHA03247; large tegument protein UL36; Provisional
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    13. XM_039088694.2 → XP_038944622.1  synaptojanin-1 isoform X7

      UniProtKB/TrEMBL
      A0A8I6AFG5
      Related
      ENSRNOP00000092411.1
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:1097 → 1494
      PHA03247; large tegument protein UL36; Provisional
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    14. XM_039088690.2 → XP_038944618.1  synaptojanin-1 isoform X1

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:1097 → 1498
      PHA03247; large tegument protein UL36; Provisional
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    15. XM_063270816.1 → XP_063126886.1  synaptojanin-1 isoform X19

      UniProtKB/TrEMBL
      A0A8I6AHP8

    16. XM_063270817.1 → XP_063126887.1  synaptojanin-1 isoform X20

      UniProtKB/TrEMBL
      A0A8I6AHP8

    17. XM_063270814.1 → XP_063126884.1  synaptojanin-1 isoform X17

      UniProtKB/TrEMBL
      A0A8I6A4X9, A6JLD5

    18. XM_063270815.1 → XP_063126885.1  synaptojanin-1 isoform X18

      UniProtKB/TrEMBL
      A6JLD5

    19. XM_063270812.1 → XP_063126882.1  synaptojanin-1 isoform X14

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8

    20. XM_063270810.1 → XP_063126880.1  synaptojanin-1 isoform X11

      UniProtKB/Swiss-Prot
      O89092, Q62910, Q62911, Q810Z8

    21. XM_039088706.2 → XP_038944634.1  synaptojanin-1 isoform X33

      UniProtKB/TrEMBL
      A6JLD6
      Conserved Domains (3) summary
      cd09098
      Location:86 → 421
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      PHA03247
      Location:607 → 1008
      PHA03247; large tegument protein UL36; Provisional
      cl17169
      Location:420 → 562
      RRM_SF; RNA recognition motif (RRM) superfamily

    22. XM_063270827.1 → XP_063126897.1  synaptojanin-1 isoform X31

      UniProtKB/TrEMBL
      A6JLD7

    23. XM_063270821.1 → XP_063126891.1  synaptojanin-1 isoform X25

      UniProtKB/TrEMBL
      D4ABN3

    24. XM_063270825.1 → XP_063126895.1  synaptojanin-1 isoform X29

      UniProtKB/TrEMBL
      A6JLD7

    25. XM_063270822.1 → XP_063126892.1  synaptojanin-1 isoform X26

      UniProtKB/TrEMBL
      A6JLD7

    26. XM_063270823.1 → XP_063126893.1  synaptojanin-1 isoform X27

      UniProtKB/TrEMBL
      A6JLD7

    27. XM_063270819.1 → XP_063126889.1  synaptojanin-1 isoform X23

      UniProtKB/TrEMBL
      D4ABN3

    28. XM_063270826.1 → XP_063126896.1  synaptojanin-1 isoform X30

      UniProtKB/TrEMBL
      A6JLD7

    29. XM_039088699.2 → XP_038944627.1  synaptojanin-1 isoform X21

      UniProtKB/TrEMBL
      D4ABN3
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      PRK07764
      Location:1110 → 1317
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    30. XM_039088700.2 → XP_038944628.1  synaptojanin-1 isoform X21

      UniProtKB/TrEMBL
      D4ABN3
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      PRK07764
      Location:1110 → 1317
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    31. XM_039088702.2 → XP_038944630.1  synaptojanin-1 isoform X22

      UniProtKB/TrEMBL
      D4ABN3
      Conserved Domains (4) summary
      cd09098
      Location:576 → 911
      INPP5c_Synj1; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1
      COG5329
      Location:100 → 523
      COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
      PRK07764
      Location:1110 → 1317
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cl17169
      Location:910 → 1052
      RRM_SF; RNA recognition motif (RRM) superfamily

    32. XM_063270818.1 → XP_063126888.1  synaptojanin-1 isoform X21

      UniProtKB/TrEMBL
      D4ABN3

    33. XM_063270828.1 → XP_063126898.1  synaptojanin-1 isoform X32

      UniProtKB/TrEMBL
      A6JLD7

    34. XM_063270824.1 → XP_063126894.1  synaptojanin-1 isoform X28

      UniProtKB/TrEMBL
      A6JLD7

    35. XM_063270820.1 → XP_063126890.1  synaptojanin-1 isoform X24

      UniProtKB/TrEMBL
      D4ABN3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q62910.3 GenPept UniProtKB/Swiss-Prot:Q62910

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