Lsm10 LSM10, U7 small nuclear RNA associated [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lsm10provided by RGD
Official Full Name: LSM10, U7 small nuclear RNA associatedprovided by RGD
Primary source: RGD:1584914
See related: Ensembl:ENSRNOG00000068296 AllianceGenome:RGD:1584914
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable U7 snRNA binding activity and histone pre-mRNA DCP binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be located in Cajal body. Predicted to be part of U7 snRNP and cytoplasmic U snRNP body. Predicted to be active in nuclear body. Orthologous to human LSM10 (LSM10, U7 small nuclear RNA associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 45.1), Adrenal (RPKM 35.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (143649817..143660391)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (138365983..138375856)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (144106339..144108703)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH140978 (e-PCR)
- UniSTS:222979

AI408354 (e-PCR)
- UniSTS:250140

RH142346 (e-PCR)
- UniSTS:231593

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables U7 snRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables U7 snRNA binding	ISO Inferred from Sequence Orthology more info
enables histone pre-mRNA DCP binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone pre-mRNA DCP binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in mRNA 3'-end processing by stem-loop binding and cleavage	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of G1/S transition of mitotic cell cycle	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Cajal body	ISO Inferred from Sequence Orthology more info
part_of U7 snRNP	ISO Inferred from Sequence Orthology more info
part_of cytoplasmic U snRNP body	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nuclear body	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: U7 snRNA-associated Sm-like protein LSm10

Names: U7 snRNP-specific Sm-like protein LSM10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.