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    CG12177 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32326, updated on 10-May-2024

    Summary

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    Official Symbol
    CG12177provided by FlyBase
    Primary source
    FLYBASE:FBgn0030510
    Locus tag
    Dmel_CG12177
    See related
    AllianceGenome:FB:FBgn0030510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12177
    Summary
    Is expressed in several structures, including embryonic Malpighian tubule; germ layer; gut section; procrystal cell; and stage 5 embryo. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG12177 in Genome Data Viewer
    Location:
    12B2-12B2; 1-45 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13677899..13680500, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13571932..13574533, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene NAD synthetase Neighboring gene Nna1 carboxypeptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo. Zeitlinger J, et al. Genes Dev, 2007 Feb 15. PMID 17322397, Free PMC Article
    2. Genomic regulatory networks and animal development. Stathopoulos A, et al. Dev Cell, 2005 Oct. PMID 16198288
    3. Systematic image-driven analysis of the spatial Drosophila embryonic expression landscape. Frise E, et al. Mol Syst Biol, 2010. PMID 20087342, Free PMC Article
    4. A core transcriptional network for early mesoderm development in Drosophila melanogaster. Sandmann T, et al. Genes Dev, 2007 Feb 15. PMID 17322403, Free PMC Article
    5. Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo. Stathopoulos A, et al. Cell, 2002 Nov 27. PMID 12464180

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables hydrolase activity, hydrolyzing N-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosylpyrimidine nucleosidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyrimidine nucleoside catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12177-PA
    CG12177-PB
    CG12177-PC
    NP_001285222.1
    NP_001285223.1
    NP_572911.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13677899..13680500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132683.2 → NP_572911.1  uncharacterized protein Dmel_CG12177, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572911.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYA1
      Related
      FBpp0073677
      Conserved Domains (1) summary
      cd02649
      Location:25 → 347
      nuc_hydro_CeIAG; nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. ...

    2. NM_001298294.1 → NP_001285223.1  uncharacterized protein Dmel_CG12177, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285223.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYA1
      Conserved Domains (1) summary
      cd02649
      Location:25 → 347
      nuc_hydro_CeIAG; nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. ...

    3. NM_001298293.1 → NP_001285222.1  uncharacterized protein Dmel_CG12177, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285222.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYA1
      Conserved Domains (1) summary
      cd02649
      Location:25 → 347
      nuc_hydro_CeIAG; nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYA1 Q9VYA1

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