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    AIMP3 aaRS-interacting multifunctional protein 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246507, updated on 10-May-2024

    Summary

    Official Symbol
    AIMP3provided by FlyBase
    Official Full Name
    aaRS-interacting multifunctional protein 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0050185
    Locus tag
    Dmel_CG30185
    See related
    AllianceGenome:FB:FBgn0050185
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey25; CG30185; CG5365; Dmel\CG30185
    Summary
    Predicted to be involved in positive regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Is expressed in organism. Orthologous to human EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See AIMP3 in Genome Data Viewer
    Location:
    59E3-59E3; 2-103 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23544024..23544901)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19431547..19432424)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 59e Neighboring gene Gustatory receptor 59f Neighboring gene wing morphogenesis defect Neighboring gene levy Neighboring gene pita Neighboring gene Death caspase-1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of aminoacyl-tRNA synthetase multienzyme complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of aminoacyl-tRNA synthetase multienzyme complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    aaRS-interacting multifunctional protein 3
    Names
    AIMP3-PA
    CG30185-PA
    aminoacyl-tRNA synthetase-interacting multifunctional protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23544024..23544901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_145193.2NP_660194.1  aaRS-interacting multifunctional protein 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_660194.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MKK1, Q8MTU4
      Related
      FBpp0071969
      Conserved Domains (1) summary
      cd10305
      Location:65166
      GST_C_AIMP3; Glutathione S-transferase C-terminal-like, alpha helical domain of Aminoacyl tRNA synthetase complex-Interacting Multifunctional Protein 3