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    Mau2 Mau2 sister chromatid cohesion factor [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41830, updated on 10-May-2024

    Summary

    Official Symbol
    Mau2provided by FlyBase
    Official Full Name
    Mau2 sister chromatid cohesion factorprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038300
    Locus tag
    Dmel_CG4203
    See related
    AllianceGenome:FB:FBgn0038300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4203; Dmel\CG4203; FBgn0038300; mau-2; Mau-2; MAU-2; MAU2
    Summary
    Predicted to enable double-stranded DNA binding activity. Predicted to be involved in axon guidance and maintenance of mitotic sister chromatid cohesion. Predicted to be located in nucleoplasm. Predicted to be part of SMC loading complex. Predicted to be active in chromatin. Orthologous to human MAU2 (MAU2 sister chromatid cohesion factor). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Mau2 in Genome Data Viewer
    Location:
    88E3-88E3; 3-56 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15209204..15211347)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11034926..11037069)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Serpin 88Ea Neighboring gene Serpin 88Eb Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Shal Interactor of Di-Leucine Motif Neighboring gene uncharacterized protein Neighboring gene mir-9383 stem loop

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in maintenance of mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in maintenance of mitotic sister chromatid cohesion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in mitotic sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of SMC loading complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SMC loading complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    Mau2 sister chromatid cohesion factor
    Names
    CG4203-PA
    Mau2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15209204..15211347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142171.4NP_650428.1  Mau2 sister chromatid cohesion factor [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650428.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VFC0
      Related
      FBpp0082507
      Conserved Domains (1) summary
      pfam10345
      Location:14563
      Cohesin_load; Cohesin loading factor