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    ATG10 autophagocytosis-associated family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819941, updated on 6-Oct-2023

    Summary

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    Gene symbol
    ATG10
    Gene description
    autophagocytosis-associated family protein
    Primary source
    Araport:AT3G07525
    Locus tag
    AT3G07525
    See related
    TAIR:AT3G07525
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATATG10; autophagy 10
    Summary
    Encodes an E1 ligase involved in autophagic vesicle formation.
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    Genomic context

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    See ATG10 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (2398951..2400603, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene glutamate receptor 1.4 Neighboring gene uncharacterized protein Neighboring gene integrator complex subunit Neighboring gene Actin-binding FH2 (formin homology 2) family protein Neighboring gene RNI-like superfamily protein Neighboring gene peroxin 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. Lenz HD, et al. Plant J, 2011 Jun. PMID 21332848
    2. The formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and implications for the sequestration of anthocyanin pigments. Pourcel L, et al. Mol Plant, 2010 Jan. PMID 20085894, Free PMC Article
    3. The ATG12-conjugating enzyme ATG10 Is essential for autophagic vesicle formation in Arabidopsis thaliana. Phillips AR, et al. Genetics, 2008 Mar. PMID 18245858, Free PMC Article
    4. A critical role of autophagy in plant resistance to necrotrophic fungal pathogens. Lai Z, et al. Plant J, 2011 Jun. PMID 21395886
    5. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_180201.3
    NM_180202.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin activating enzyme activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ubiquitin-like protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within autophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular pigment accumulation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to nitrogen starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of autophagosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to carbon starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    autophagocytosis-associated family protein
    NP_850532.1
    • autophagy 10 (ATG10); CONTAINS InterPro DOMAIN/s: Autophagy-related protein 3 (InterPro:IPR007135); Has 423 Blast hits to 423 proteins in 154 species: Archae - 0; Bacteria - 0; Metazoa - 229; Fungi - 97; Plants - 56; Viruses - 0; Other Eukaryotes - 41 (source: NCBI BLink).
    NP_850533.1
    • autophagy 10 (ATG10); CONTAINS InterPro DOMAIN/s: Autophagy-related protein 3 (InterPro:IPR007135); Has 420 Blast hits to 420 proteins in 152 species: Archae - 0; Bacteria - 0; Metazoa - 229; Fungi - 94; Plants - 56; Viruses - 0; Other Eukaryotes - 41 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2398951..2400603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180201.3 → NP_850532.1  autophagocytosis-associated family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850532.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JEH1, Q8VZ52
      UniProtKB/TrEMBL
      A0A178V6V0
      Conserved Domains (1) summary
      pfam03987
      Location:17 → 222
      Autophagy_act_C; Autophagocytosis associated protein, active-site domain

    2. NM_180202.1 → NP_850533.1  autophagocytosis-associated family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850533.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V865, A0A5S9XA33
      Conserved Domains (1) summary
      pfam03987
      Location:17 → 223
      Autophagy_act_C; Autophagocytosis associated protein, active-site domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VZ52.1

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