Pcare photoreceptor cilium actin regulator [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pcareprovided by RGD
Official Full Name: photoreceptor cilium actin regulatorprovided by RGD
Primary source: RGD:1304963
See related: Ensembl:ENSRNOG00000008942 AllianceGenome:RGD:1304963
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1304963
Summary: Predicted to be involved in photoreceptor cell outer segment organization and protein localization to photoreceptor outer segment. Predicted to be located in cilium. Predicted to be active in photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in retinitis pigmentosa 54. Orthologous to human PCARE (photoreceptor cilium actin regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 84.3) and Muscle (RPKM 29.1) See more
Orthologs: human mouse all
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Genomic context

Location:: 6q14

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (29469232..29478541)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (23749700..23758424)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (23337507..23346232)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in photoreceptor cell outer segment organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within photoreceptor cell outer segment organization	ISO Inferred from Sequence Orthology more info
involved_in protein localization to photoreceptor outer segment	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein localization to photoreceptor outer segment	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cilium	ISO Inferred from Sequence Orthology more info
located_in cone photoreceptor outer segment	ISO Inferred from Sequence Orthology more info
is_active_in photoreceptor inner segment	IBA Inferred from Biological aspect of Ancestor more info
located_in photoreceptor inner segment	ISO Inferred from Sequence Orthology more info
is_active_in photoreceptor outer segment	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: photoreceptor cilium actin regulator

Names: uncharacterized protein C2orf71 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001399236.1 → NP_001386165.1 photoreceptor cilium actin regulator

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

Conserved Domains (1) summary

pfam15449
Location:1 → 1246

Retinal; Retinal protein