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    CG14505 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37098, updated on 10-May-2024

    Summary

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    Official Symbol
    CG14505provided by FlyBase
    Primary source
    FLYBASE:FBgn0034327
    Locus tag
    Dmel_CG14505
    See related
    AllianceGenome:FB:FBgn0034327
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14505
    Summary
    Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be active in cytoplasm. Orthologous to human GSKIP (GSK3B interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG14505 in Genome Data Viewer
    Location:
    55C2-55C2; 2-85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18302945..18303977, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14190450..14191482, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene scribbler Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Transport and Golgi organization 8 Neighboring gene long non-coding RNA:CR42736

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Vartiainen S, et al. Dis Model Mech, 2014 Jun. PMID 24812436, Free PMC Article
    2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14505-PB
    CG14505-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18302945..18303977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001043093.2 → NP_001036558.1  uncharacterized protein Dmel_CG14505, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036558.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V8F3
      UniProtKB/TrEMBL
      A0A0B4K841
      Conserved Domains (1) summary
      pfam05303
      Location:15 → 116
      DUF727; Protein of unknown function (DUF727)

    2. NM_001259475.1 → NP_001246404.1  uncharacterized protein Dmel_CG14505, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246404.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V8F3
      UniProtKB/TrEMBL
      A0A0B4K841
      Conserved Domains (1) summary
      pfam05303
      Location:15 → 116
      DUF727; Protein of unknown function (DUF727)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K841 A0A0B4K841
    Q9V8F3.1 Q9V8F3

    Gene LinkOut

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