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    CG42613 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42269, updated on 10-May-2024

    Summary

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    Official Symbol
    CG42613provided by FlyBase
    Primary source
    FLYBASE:FBgn0261262
    Locus tag
    Dmel_CG42613
    See related
    AllianceGenome:FB:FBgn0261262
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14289; CG31149; CG31222; CG5449; CT17110; CT33918; dLev-10; Dmel\CG42613; tld-like
    Old locus tag
    Dmel_CG31149; Dmel_CG31222
    Summary
    Is expressed in adult head. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG42613 in Genome Data Viewer
    Location:
    91D5-91E1; 3-65 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18929196..18978088)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14754918..14803810)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Xrp1 Neighboring gene Mitochondrial pyruvate carrier Neighboring gene uncharacterized protein Neighboring gene Smu1 spliceosomal factor Neighboring gene eucalyptus Neighboring gene deoxyribonucleoside kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity. Mallik M, et al. J Cell Biol, 2018 Nov 5. PMID 30209068, Free PMC Article
    2. t-GRASP, a targeted GRASP for assessing neuronal connectivity. Shearin HK, et al. J Neurosci Methods, 2018 Aug 1. PMID 29792886, Free PMC Article
    3. A Regulatory Response to Ribosomal Protein Mutations Controls Translation, Growth, and Cell Competition. Lee CH, et al. Dev Cell, 2018 Aug 20. PMID 30078730, Free PMC Article
    4. Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster. Ma L, et al. PLoS One, 2015. PMID 25798821, Free PMC Article
    5. Sequoia, a tramtrack-related zinc finger protein, functions as a pan-neural regulator for dendrite and axon morphogenesis in Drosophila. Brenman JE, et al. Dev Cell, 2001 Nov. PMID 11709187

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42613-PE
    CG42613-PF
    CG42613-PG
    CG42613-PH
    CG42613-PI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18929196..18978088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260256.1 → NP_001247185.1  uncharacterized protein Dmel_CG42613, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247185.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K760
      Conserved Domains (2) summary
      cd00041
      Location:421 → 541
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:987 → 1022
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    2. NM_001414099.1 → NP_001401046.1  uncharacterized protein Dmel_CG42613, isoform I [Drosophila melanogaster]

      Status: REVIEWED

    3. NM_169844.4 → NP_732390.3  uncharacterized protein Dmel_CG42613, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732390.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE20
      Conserved Domains (2) summary
      cd00041
      Location:388 → 508
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:954 → 989
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    4. NM_001260258.1 → NP_001247187.1  uncharacterized protein Dmel_CG42613, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247187.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6C8
      Conserved Domains (2) summary
      cd00041
      Location:388 → 508
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:954 → 989
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

    5. NM_001260257.2 → NP_001247186.1  uncharacterized protein Dmel_CG42613, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247186.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K686, D0IQI1
      Conserved Domains (3) summary
      cd00041
      Location:78 → 198
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00112
      Location:644 → 679
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cl00049
      Location:17 → 61
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K686 A0A0B4K686
    A0A0B4K6C8 A0A0B4K6C8
    A0A0B4K760 A0A0B4K760
    Q961I3 Q961I3
    Q9VE20 Q9VE20

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