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    ND-B17 NADH dehydrogenase (ubiquinone) B17 subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34925, updated on 10-May-2024

    Summary

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    Official Symbol
    ND-B17provided by FlyBase
    Official Full Name
    NADH dehydrogenase (ubiquinone) B17 subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0001989
    Locus tag
    Dmel_CG13240
    See related
    AllianceGenome:FB:FBgn0001989
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM23292; BG:DS09217.1; CG13240; Dmel\CG13240; dNDUFB6; l(2)35Di; NB7M; NDUFB6
    Summary
    Predicted to enable NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut; embryonic/larval midgut primordium; and spermatozoon. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See ND-B17 in Genome Data Viewer
    Location:
    35D4-35D4; 2-51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15749319..15751078, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15749319..15751078, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cyclin E Neighboring gene long non-coding RNA:CR44974 Neighboring gene antisense RNA:CR44866 Neighboring gene small nuclear RNA U5 at 35D Neighboring gene Mtr4 helicase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Mitochondria-Targeted Plastoquinone-Derivative SkQ1 Promotes Health and Increases Drosophila melanogaster Longevity in Various Environments. Tsybul'ko E, et al. J Gerontol A Biol Sci Med Sci, 2017 Apr 1. PMID 27166099, Free PMC Article
    2. Cropped, Drosophila transcription factor AP-4, controls tracheal terminal branching and cell growth. Wong MM, et al. BMC Dev Biol, 2015 Apr 15. PMID 25888431, Free PMC Article
    3. Genetic analysis of speciation by means of introgression into Drosophila melanogaster. Sawamura K, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706624, Free PMC Article
    4. A family of snail-related zinc finger proteins regulates two distinct and parallel mechanisms that mediate Drosophila neuroblast asymmetric divisions. Cai Y, et al. EMBO J, 2001 Apr 2. PMID 11285234, Free PMC Article
    5. The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster. Hossain KFB, et al. Sci Rep, 2022 Dec 27. PMID 36575244, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitochondrial electron transport, NADH to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial respiratory chain complex I IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase (ubiquinone) B17 subunit
    Names
    CG13240-PA
    CG13240-PC
    NADH ubiquinone oxidoreductase B17
    NADH-ubiquinone oxidoreductase B17 subunit
    NADH:ubiquinone oxidoreductase B17 subunit
    ND-B17-PA
    ND-B17-PC
    lethal (2) 35Di

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15749319..15751078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165126.3 → NP_723927.2  NADH dehydrogenase (ubiquinone) B17 subunit, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723927.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP37, Q9V3W2
      Conserved Domains (1) summary
      pfam09782
      Location:9 → 160
      NDUF_B6; NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit

    2. NM_135921.4 → NP_609765.1  NADH dehydrogenase (ubiquinone) B17 subunit, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609765.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP37, Q9V3W2
      Related
      FBpp0080329
      Conserved Domains (1) summary
      pfam09782
      Location:9 → 160
      NDUF_B6; NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V3W2 Q9V3W2

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