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    CG4953 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34373, updated on 10-May-2024

    Summary

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    Official Symbol
    CG4953provided by FlyBase
    Primary source
    FLYBASE:FBgn0032204
    Locus tag
    Dmel_CG4953
    See related
    AllianceGenome:FB:FBgn0032204
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4953; TRAPPC13
    Summary
    Predicted to be involved in Golgi vesicle transport. Located in Golgi apparatus. Part of TRAPPIII protein complex. Is expressed in adult head and organism. Orthologous to human TRAPPC13 (trafficking protein particle complex subunit 13). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG4953 in Genome Data Viewer
    Location:
    31B1-31B1; 2-40 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10266703..10268748)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10266703..10268748)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene REPTOR-binding partner Neighboring gene MOB kinase activator 3 Neighboring gene uncharacterized protein Neighboring gene Multi-substrate lipid kinase Neighboring gene trunk

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1. Galindo A, et al. EMBO J, 2021 Jun 15. PMID 34018214, Free PMC Article
    2. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. Riedel F, et al. J Cell Biol, 2018 Feb 5. PMID 29273580, Free PMC Article
    3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of TRAPPIII protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TRAPPIII protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4953-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10266703..10268748
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135521.6 → NP_609365.3  uncharacterized protein Dmel_CG4953 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609365.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95TN1, Q9VL12
      Related
      FBpp0079574
      Conserved Domains (1) summary
      pfam06159
      Location:64 → 289
      DUF974; Protein of unknown function (DUF974)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95TN1.1 Q95TN1

    Gene LinkOut

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