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    indra [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38159, updated on 10-May-2024

    Summary

    Official Symbol
    indraprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035213
    Locus tag
    Dmel_CG2199
    See related
    AllianceGenome:FB:FBgn0035213
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2199; Dmel\CG2199; FBpp0072605
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut; extended germ band embryo; foregut primordium; and spermatozoon. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See indra in Genome Data Viewer
    Location:
    61F7-61F7; 3-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1339460..1342403, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1339460..1342403, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mitotic spindle density 1 Neighboring gene mitotic spindle density 5 Neighboring gene Hydroxymethylbilane synthase Neighboring gene Protein tyrosine phosphatase 61F Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Glutamic acid-CTC 3-1 Neighboring gene roughoid

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rDNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in maintenance of rDNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    indra
    Names
    CG2199-PA
    CG2199-PB
    CG2199-PC
    indra-PA
    indra-PB
    indra-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1339460..1342403 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167873.2NP_728599.1  indra, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728599.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9UNC2, H0RNL4, M9PBH8, Q29R03, Q6NNC3, Q8IRH5, Q960W3, Q9W0G3
      Related
      FBpp0072605
      Conserved Domains (1) summary
      sd00019
      Location:418439
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_138260.5NP_612104.1  indra, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612104.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IRH5
      UniProtKB/TrEMBL
      M9PBH8
      Related
      FBpp0072606
      Conserved Domains (1) summary
      sd00019
      Location:409430
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001274323.1NP_001261252.1  indra, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261252.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IRH5
      UniProtKB/TrEMBL
      M9PBH8
      Conserved Domains (1) summary
      sd00019
      Location:409430
      ZF_C2H2; C2H2 Zn finger [structural motif]