Sprr2e small proline-rich protein 2E [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sprr2eprovided by MGI
Official Full Name: small proline-rich protein 2Eprovided by MGI
Primary source: MGI:MGI:1330346
See related: Ensembl:ENSMUSG00000055030 AllianceGenome:MGI:1330346
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Acts upstream of or within response to estradiol. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward stomach adult (RPKM 4.6) See more
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Genomic context

Location:: 3 F1; 3 40.14 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (92259450..92260757)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (92352143..92353449)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables lipid binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of skin epidermis	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in epidermis development	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within keratinization	IEA Inferred from Electronic Annotation more info
involved_in keratinocyte differentiation	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within response to estradiol	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cornified envelope	ISO Inferred from Sequence Orthology more info
located_in cornified envelope	NAS Non-traceable Author Statement more info	PubMed
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in secretory granule	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: small proline-rich protein 2E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.