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    Ubl7 ubiquitin-like 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300744, updated on 20-Apr-2024

    Summary

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    Official Symbol
    Ubl7provided by RGD
    Official Full Name
    ubiquitin-like 7provided by RGD
    Primary source
    RGD:1303055
    See related
    Ensembl:ENSRNOG00000007442 AllianceGenome:RGD:1303055
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Bmsc-UbP
    Summary
    Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. Orthologous to human UBL7 (ubiquitin like 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 109.7), Brain (RPKM 102.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ubl7 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (67217151..67236224)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (58321279..58340353)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (62696557..62715694)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene AT-rich interaction domain 3B Neighboring gene uncharacterized LOC134480188 Neighboring gene uncharacterized LOC134480057 Neighboring gene semaphorin 7A (John Milton Hagen blood group) Neighboring gene uncharacterized LOC134480058 Neighboring gene uncharacterized LOC103693105

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning and identification of a novel ubiquitin-like protein, BMSC-UbP, from human bone marrow stromal cells. Liu S, et al. Immunol Lett, 2003 Apr 3. PMID 12644319
    2. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94284

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables molecular adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables polyubiquitin modification-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-like protein 7
    Names
    bone marrow stromal cell-derived ubiquitin-like protein
    ubiquitin-like 7 (bone marrow stromal cell-derived)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004247.2 → NP_001004247.1  ubiquitin-like protein 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8I5ZWS3, Q6AY24
      Conserved Domains (2) summary
      cd14326
      Location:347 → 376
      UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
      cd01815
      Location:7 → 98
      Ubl_UBL7; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 7 (UBL7) and similar proteins

    2. NM_001413519.1 → NP_001400448.1  ubiquitin-like protein 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      Q6AY24

    3. NM_001413520.1 → NP_001400449.1  ubiquitin-like protein 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      Q6AY24
      Related
      ENSRNOP00000083337.1, ENSRNOT00000117925.1

    4. NM_001429274.1 → NP_001416203.1  ubiquitin-like protein 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    5. NM_001429275.1 → NP_001416204.1  ubiquitin-like protein 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    6. NM_001429276.1 → NP_001416205.1  ubiquitin-like protein 7 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    7. NM_001429277.1 → NP_001416206.1  ubiquitin-like protein 7 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    8. NM_001429278.1 → NP_001416207.1  ubiquitin-like protein 7 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    9. NM_001429279.1 → NP_001416208.1  ubiquitin-like protein 7 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    10. NM_001429280.1 → NP_001416209.1  ubiquitin-like protein 7 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    11. NM_001429281.1 → NP_001416210.1  ubiquitin-like protein 7 isoform 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    12. NM_001429282.1 → NP_001416211.1  ubiquitin-like protein 7 isoform 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    13. NM_001429283.1 → NP_001416212.1  ubiquitin-like protein 7 isoform 7

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      67217151..67236224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081089.2 → XP_038937017.1  ubiquitin-like protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZWS3, Q6AY24
      Conserved Domains (2) summary
      cd14326
      Location:347 → 376
      UBA_UBL7; UBA domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
      cd01815
      Location:7 → 98
      Ubl_UBL7; ubiquitin-like (Ubl) domain found in ubiquitin-like protein 7 (UBL7) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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