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    Mamstr MEF2 activating motif and SAP domain containing transcriptional regulator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691041, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mamstrprovided by RGD
    Official Full Name
    MEF2 activating motif and SAP domain containing transcriptional regulatorprovided by RGD
    Primary source
    RGD:1588652
    See related
    Ensembl:ENSRNOG00000024580 AllianceGenome:RGD:1588652
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of myotube differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAMSTR (MEF2 activating motif and SAP domain containing transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 52.6), Heart (RPKM 13.6) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Mamstr in Genome Data Viewer
    Location:
    1q22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (105246172..105252759)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (96109715..96116295)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101621733..101628379)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene izumo sperm-oocyte fusion 1 Neighboring gene Ras interacting protein 1 Neighboring gene fucosyltransferase 2 Neighboring gene secretory blood group 1 Neighboring gene netrin 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    MEF2 activating motif and SAP domain containing transcriptional regulator; MEF2-activating motif and SAP domain-containing transcriptional regulator

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      105246172..105252759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001076631.8XP_001076631.2  MEF2-activating motif and SAP domain-containing transcriptional regulator

      See identical proteins and their annotated locations for XP_001076631.2

      UniProtKB/TrEMBL
      D3ZHU3
      Related
      ENSRNOP00000053047.2
      Conserved Domains (1) summary
      pfam02037
      Location:166195
      SAP; SAP domain
    2. XM_006229211.5XP_006229273.1  MEF2-activating motif and SAP domain-containing transcriptional regulator

      See identical proteins and their annotated locations for XP_006229273.1

      UniProtKB/TrEMBL
      D3ZHU3
      Conserved Domains (1) summary
      pfam02037
      Location:166195
      SAP; SAP domain