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    Rassf8 Ras association domain family member 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312846, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Rassf8provided by RGD
    Official Full Name
    Ras association domain family member 8provided by RGD
    Primary source
    RGD:1308820
    See related
    Ensembl:ENSRNOG00000015986 AllianceGenome:RGD:1308820
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308820
    Summary
    Predicted to be involved in signal transduction. Orthologous to human RASSF8 (Ras association domain family member 8). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 159.7), Muscle (RPKM 129.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rassf8 in Genome Data Viewer
    Location:
    4q44
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (180447050..180528792)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (178716110..178798042)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (180059020..180135924)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486868 Neighboring gene large ribosomal subunit protein eL31-like Neighboring gene basic helix-loop-helix family, member e41 Neighboring gene uncharacterized LOC102549898 Neighboring gene sarcospan

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of key genes and pathways associated with cholangiocarcinoma development based on weighted gene correlation network analysis. Liu J, et al. PeerJ, 2019. PMID 31687280, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras association domain-containing protein 8
    Names
    Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
    Ras association (RalGDS/AF-6) domain family 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191753.1 → NP_001178682.1  ras association domain-containing protein 8

      See identical proteins and their annotated locations for NP_001178682.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      D4AAU5
      Conserved Domains (1) summary
      smart00314
      Location:1 → 81
      RA; Ras association (RalGDS/AF-6) domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      180447050..180528792
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286174.1 → XP_063142244.1  ras association domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      D4AAU5

    2. XM_017592668.3 → XP_017448157.1  ras association domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      D4AAU5
      Conserved Domains (1) summary
      smart00314
      Location:1 → 81
      RA; Ras association (RalGDS/AF-6) domain

    3. XM_006237659.5 → XP_006237721.1  ras association domain-containing protein 8 isoform X1

      See identical proteins and their annotated locations for XP_006237721.1

      UniProtKB/TrEMBL
      D4AAU5
      Related
      ENSRNOP00000021623.5
      Conserved Domains (1) summary
      smart00314
      Location:1 → 81
      RA; Ras association (RalGDS/AF-6) domain

    4. XM_063286173.1 → XP_063142243.1  ras association domain-containing protein 8 isoform X1

      UniProtKB/TrEMBL
      D4AAU5
    Nucleotide Protein Strain
    Heading Accession and Version

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