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    LHX5 LIM homeobox 5 [ Gallus gallus (chicken) ]

    Gene ID: 771259, updated on 5-Mar-2024

    Summary

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    Symbol
    LHX5provided by CGNC
    Full Name
    LIM homeobox 5provided by CGNC
    Primary source
    CGNC:6292
    See related
    Ensembl:ENSGALG00010000445
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See LHX5 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (12575498..12583138)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (12587668..12595313)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 19 Neighboring gene uncharacterized LOC124417238 Neighboring gene serine dehydratase like Neighboring gene phospholipase B domain containing 2 Neighboring gene solute carrier family 8 member B1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The expression of LIM-homeobox genes, Lhx1 and Lhx5, in the forebrain is essential for neural retina differentiation. Inoue J, et al. Dev Growth Differ, 2013 Sep. PMID 24024588
    2. Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Kawaue T, et al. Biol Open, 2012 Nov 15. PMID 23213388, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LIM/homeobox protein Lhx5
    Names
    LIM homeobox protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001320906.1 → NP_001307835.1  LIM/homeobox protein Lhx5

      Status: PROVISIONAL

      Source sequence(s)
      AB485718
      UniProtKB/TrEMBL
      A0A140JTJ9, A0A8V0X5B1, E1BQX0
      Related
      ENSGALP00010000493.1, ENSGALT00010000929.1
      Conserved Domains (3) summary
      cd09367
      Location:5 → 56
      LIM1_Lhx1_Lhx5; The first LIM domain of Lhx1 (also known as Lim1) and Lhx5
      cd09375
      Location:64 → 119
      LIM2_Lhx1_Lhx5; The second LIM domain of Lhx1 (also known as Lim1) and Lhx5
      pfam00046
      Location:183 → 237
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      12575498..12583138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004934489.5 → XP_004934546.1  LIM/homeobox protein Lhx5 isoform X1

      Conserved Domains (3) summary
      cd09367
      Location:5 → 56
      LIM1_Lhx1_Lhx5; The first LIM domain of Lhx1 (also known as Lim1) and Lhx5
      cd09375
      Location:64 → 119
      LIM2_Lhx1_Lhx5; The second LIM domain of Lhx1 (also known as Lim1) and Lhx5
      pfam00046
      Location:183 → 236
      Homeobox; Homeobox domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12587668..12595313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928268.1 → XP_046784224.1  LIM/homeobox protein Lhx5 isoform X1

    Nucleotide Protein
    Heading Accession and Version

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    Research Materials