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    Gcc1 golgi coiled coil 1 [ Mus musculus (house mouse) ]

    Gene ID: 74375, updated on 21-May-2024

    Summary

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    Official Symbol
    Gcc1provided by MGI
    Official Full Name
    golgi coiled coil 1provided by MGI
    Primary source
    MGI:MGI:1921625
    See related
    Ensembl:ENSMUSG00000029708 AllianceGenome:MGI:1921625
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932417P04Rik
    Summary
    Predicted to be located in cytoplasm and membrane. Predicted to be active in Golgi apparatus. Orthologous to human GCC1 (GRIP and coiled-coil domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 4.9), colon adult (RPKM 3.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gcc1 in Genome Data Viewer
    Location:
    6 A3.3; 6 11.99 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (28413784..28424152, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (28416603..28421724, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6530409C15 gene Neighboring gene zinc finger protein 800 Neighboring gene STARR-seq mESC enhancer starr_15407 Neighboring gene STARR-seq mESC enhancer starr_15408 Neighboring gene kelch domain containing pseudogene Neighboring gene STARR-seq mESC enhancer starr_15409 Neighboring gene STARR-positive B cell enhancer mm9_chr6:28371614-28371915 Neighboring gene Pax4 5' regulatory region Neighboring gene ADP-ribosylation factor 5 Neighboring gene fascin actin-bundling protein 3 Neighboring gene paired box 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Fenske TS, et al. Cancer Res, 2006 May 15. PMID 16707424
    2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GRIP and coiled-coil domain-containing protein 1
    Names
    Golgi coiled coil protein 1
    golgi coiled-coil protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427121.1 → NP_001414050.1  GRIP and coiled-coil domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC068608
      UniProtKB/Swiss-Prot
      Q8CCR3, Q9D4H2
      Related
      ENSMUSP00000067395.7, ENSMUST00000064377.7

    2. NM_028900.5 → NP_083176.3  GRIP and coiled-coil domain-containing protein 1

      See identical proteins and their annotated locations for NP_083176.3

      Status: VALIDATED

      Source sequence(s)
      AC068608
      Consensus CDS
      CCDS19951.1
      UniProtKB/Swiss-Prot
      Q8CCR3, Q9D4H2
      Related
      ENSMUSP00000087997.4, ENSMUST00000090511.4
      Conserved Domains (2) summary
      pfam01465
      Location:721 → 763
      GRIP; GRIP domain
      cl19219
      Location:389 → 506
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      28413784..28424152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D4H2.2 GenPept UniProtKB/Swiss-Prot:Q9D4H2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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