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    Tmem161a transmembrane protein 161A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364535, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Tmem161aprovided by RGD
    Official Full Name
    transmembrane protein 161Aprovided by RGD
    Primary source
    RGD:1307703
    See related
    Ensembl:ENSRNOG00000020390 AllianceGenome:RGD:1307703
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307703
    Summary
    Predicted to be involved in several processes, including cellular response to UV; regulation of response to DNA damage stimulus; and response to retinoic acid. Predicted to be integral component of membrane. Orthologous to human TMEM161A (transmembrane protein 161A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 88.5), Heart (RPKM 53.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem161a in Genome Data Viewer
    Location:
    16p14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19272433..19282173, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19237638..19248151, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20985841..20996351, complement)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene SURP and G patch domain containing 2 Neighboring gene U6 spliceosomal RNA Neighboring gene armadillo repeat containing 6 Neighboring gene solute carrier family 25, member 42 Neighboring gene myocyte enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X-associated ankyrin-containing protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. AROS-29 is involved in adaptive response to oxidative stress. Montesano Gesualdi N, et al. Free Radic Res, 2006 May. PMID 16551573
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cellular response to UV ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to oxidative stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of DNA repair ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to retinoic acid ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 161A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108874.2 → NP_001102344.1  transmembrane protein 161A precursor

      See identical proteins and their annotated locations for NP_001102344.1

      Status: PROVISIONAL

      Source sequence(s)
      BC161989
      UniProtKB/TrEMBL
      B1WC35, F7EZW5
      Related
      ENSRNOP00000027639.6, ENSRNOT00000027639.7
      Conserved Domains (1) summary
      pfam10268
      Location:2 → 476
      Tmemb_161AB; Predicted transmembrane protein 161AB

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      19272433..19282173 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275592.1 → XP_063131662.1  transmembrane protein 161A isoform X5

    2. XM_039094719.2 → XP_038950647.1  transmembrane protein 161A isoform X3

      UniProtKB/TrEMBL
      F7EZW5
      Conserved Domains (1) summary
      pfam10268
      Location:2 → 452
      Tmemb_161AB; Predicted transmembrane protein 161AB

    3. XM_006252914.3 → XP_006252976.1  transmembrane protein 161A isoform X6

      Conserved Domains (1) summary
      pfam10268
      Location:2 → 373
      Tmemb_161AB; Predicted transmembrane protein 161AB

    4. XM_008771143.4 → XP_008769365.2  transmembrane protein 161A isoform X1

      Conserved Domains (1) summary
      pfam10268
      Location:2 → 325
      Tmemb_161AB; Predicted transmembrane protein 161AB

    5. XM_039094717.2 → XP_038950645.1  transmembrane protein 161A isoform X1

      Conserved Domains (1) summary
      pfam10268
      Location:2 → 325
      Tmemb_161AB; Predicted transmembrane protein 161AB

    6. XM_063275593.1 → XP_063131663.1  transmembrane protein 161A isoform X7

    7. XM_063275591.1 → XP_063131661.1  transmembrane protein 161A isoform X4

      UniProtKB/TrEMBL
      F7EZW5

    8. XM_006252913.4 → XP_006252975.1  transmembrane protein 161A isoform X2

      UniProtKB/TrEMBL
      A0A8I6GJF5, F7EZW5
      Related
      ENSRNOP00000092050.1
      Conserved Domains (1) summary
      pfam10268
      Location:40 → 453
      Tmemb_161AB; Predicted transmembrane protein 161AB

    9. XM_063275594.1 → XP_063131664.1  transmembrane protein 161A isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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