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    Calml3 calmodulin-like 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307100, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Calml3provided by RGD
    Official Full Name
    calmodulin-like 3provided by RGD
    Primary source
    RGD:1305499
    See related
    Ensembl:ENSRNOG00000031955 AllianceGenome:RGD:1305499
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable calcium ion binding activity and enzyme regulator activity. Predicted to be involved in regulation of catalytic activity. Orthologous to human CALML3 (calmodulin like 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 113.7), Testes (RPKM 68.8) and 2 other tissues See more
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    Genomic context

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    See Calml3 in Genome Data Viewer
    Location:
    17q12.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (71329438..71333068)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (66419844..66423083)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (70070458..70073697)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103694125 Neighboring gene calmodulin-like 5 Neighboring gene uncharacterized LOC120097832 Neighboring gene nucleolar pre-rRNA processing protein NIP7, pseudogene 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Dynamic network biomarker indicates pulmonary metastasis at the tipping point of hepatocellular carcinoma. Yang B, et al. Nat Commun, 2018 Feb 14. PMID 29445139, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in positive regulation of ryanodine-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    calmodulin-like protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012054.1 → NP_001012054.1  calmodulin-like protein 3

      See identical proteins and their annotated locations for NP_001012054.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086350
      UniProtKB/Swiss-Prot
      Q5U206
      UniProtKB/TrEMBL
      A6JLQ5
      Conserved Domains (1) summary
      PTZ00184
      Location:1 → 149
      PTZ00184; calmodulin; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      71329438..71333068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276491.1 → XP_063132561.1  calmodulin-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q5U206
      UniProtKB/TrEMBL
      A6JLQ5

    2. XM_006254208.5 → XP_006254270.1  calmodulin-like protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006254270.1

      UniProtKB/Swiss-Prot
      Q5U206
      UniProtKB/TrEMBL
      A6JLQ5
      Related
      ENSRNOP00000043121.3
      Conserved Domains (1) summary
      PTZ00184
      Location:1 → 149
      PTZ00184; calmodulin; Provisional

    3. XM_063276492.1 → XP_063132562.1  calmodulin-like protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q5U206
      UniProtKB/TrEMBL
      A6JLQ5
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U206.1 GenPept UniProtKB/Swiss-Prot:Q5U206

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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