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    Ripply1 ripply transcriptional repressor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680702, updated on 5-Mar-2024

    Summary

    Official Symbol
    Ripply1provided by RGD
    Official Full Name
    ripply transcriptional repressor 1provided by RGD
    Primary source
    RGD:1588264
    See related
    Ensembl:ENSRNOG00000061101 AllianceGenome:RGD:1588264
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in embryonic pattern specification and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including Notch signaling pathway; bone morphogenesis; and somite rostral/caudal axis specification. Predicted to be active in nucleus. Orthologous to human RIPPLY1 (ripply transcriptional repressor 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Liver (RPKM 12.7), Kidney (RPKM 4.3) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Ripply1 in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (108225333..108231537, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (103436731..103440904, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (111099420..111114835, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 8B Neighboring gene ribosomal protein S4, X-linked, pseudogene 12 Neighboring gene claudin 2 Neighboring gene MORC family CW-type zinc finger 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    protein ripply1
    Names
    ripply1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      108225333..108231537 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280530.1XP_063136600.1  protein ripply1 isoform X2

    2. XM_039100456.2XP_038956384.1  protein ripply1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6B0B3
      Related
      ENSRNOP00000094355.1
      Conserved Domains (1) summary
      pfam14998
      Location:116190
      Ripply; Transcription Regulator