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    Tafa1 TAFA chemokine like family member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500266, updated on 5-Mar-2024

    Summary

    Symbol
    Tafa1provided by RGD
    Full Name
    TAFA chemokine like family member 1provided by RGD
    Primary source
    RGD:1563030
    See related
    Ensembl:ENSRNOG00000070575 AllianceGenome:RGD:1563030
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam19a1; RGD1563030
    Summary
    Predicted to enable receptor ligand activity. Predicted to be involved in neuroblast differentiation; regulation of neuroblast proliferation; and regulation of signaling receptor activity. Predicted to be located in endoplasmic reticulum and extracellular space. Orthologous to human TAFA1 (TAFA chemokine like family member 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 60.1), Spleen (RPKM 18.8) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Tafa1 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (130294659..130799139)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (128738028..129244223)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (128818468..128942088)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene NOP2 nucleolar protein, pseudogene 4 Neighboring gene uncharacterized LOC102549269 Neighboring gene ribosome biogenesis regulator 1 homolog, pseudogene 7 Neighboring gene nucleoporin 50, pseudogene 1 Neighboring gene uncharacterized LOC120102500 Neighboring gene uncharacterized LOC120102499 Neighboring gene RNA, U6 small nuclear 131 Neighboring gene TAFA chemokine like family member 4 Neighboring gene uncharacterized LOC134486820 Neighboring gene uncharacterized LOC134486821

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables receptor ligand activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in neuroblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TAFA chemokine like family member 1; chemokine-like protein TAFA-1
    Names
    family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
    family with sequence similarity 19 member A1, C-C motif chemokine like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      130294659..130799139
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109030.2XP_038964958.1  chemokine-like protein TAFA-1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZYE4
      Conserved Domains (1) summary
      pfam12020
      Location:41129
      TAFA; TAFA family
    2. XM_039109032.2XP_038964960.1  chemokine-like protein TAFA-1 isoform X1

      Conserved Domains (1) summary
      pfam12020
      Location:40128
      TAFA; TAFA family
    3. XM_039109031.2XP_038964959.1  chemokine-like protein TAFA-1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZYE4
      Related
      ENSRNOP00000083056.1
      Conserved Domains (1) summary
      pfam12020
      Location:41129
      TAFA; TAFA family