U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    VDAC1 voltage dependent anion channel 1 [ Bos taurus (cattle) ]

    Gene ID: 282119, updated on 6-Jun-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    VDAC1provided by VGNC
    Official Full Name
    voltage dependent anion channel 1provided by VGNC
    Primary source
    VGNC:VGNC:36782
    See related
    BGD:BT26720; Ensembl:ENSBTAG00000013113
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See VDAC1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (45663910..45690712, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene follistatin like 4 Neighboring gene uncharacterized LOC112447416 Neighboring gene uncharacterized LOC132345820 Neighboring gene chromosome 7 C5orf15 homolog Neighboring gene transcription factor 7 Neighboring gene S-phase kinase associated protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Location of the dicyclohexylcarbodiimide-reactive glutamate residue in the bovine heart mitochondrial porin. De Pinto V, et al. J Biol Chem, 1993 Jun 15. PMID 7685355
    2. Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes. Dermietzel R, et al. Proc Natl Acad Sci U S A, 1994 Jan 18. PMID 7507248, Free PMC Article
    3. Localisation and function of voltage-dependent anion channels (VDAC) in bovine spermatozoa. Triphan X, et al. Pflugers Arch, 2008 Jan. PMID 17647012
    4. Relationship between expression of voltage-dependent anion channel (VDAC) isoforms and type of hexokinase binding sites on brain mitochondria. Poleti MD, et al. J Mol Neurosci, 2010 May. PMID 19688190
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Multiple spots on 2D gel representing VDAC1 protein forms with different isoelectric points.
      Title: Relationship between expression of voltage-dependent anion channel (VDAC) isoforms and type of hexokinase binding sites on brain mitochondria.
    2. Results describe the expression of voltage-dependent anion channel isoforms in rat, bovine, and chicken brain mitochondria, and suggest that the nature of hexokinase binding site is not determined by the expression of a single VDAC isoform.
      Title: Relationship between expression of voltage-dependent anion channel (VDAC) isoforms and type of hexokinase binding sites on brain mitochondria.
    3. Suggest that VDAC1 participates in volume regulatory processes in spermatozoa.
      Title: Localisation and function of voltage-dependent anion channels (VDAC) in bovine spermatozoa.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated monoatomic anion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic anion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    voltage-dependent anion-selective channel protein 1
    Names
    BR1-VDAC
    VDAC-1
    brain-derived voltage-dependent anion channel 1
    plasmalemmal porin

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174485.4 → NP_776910.2  voltage-dependent anion-selective channel protein 1

      See identical proteins and their annotated locations for NP_776910.2

      Status: PROVISIONAL

      Source sequence(s)
      BC102113
      UniProtKB/TrEMBL
      A0A3Q1MJQ7
      Related
      ENSBTAP00000017430.4, ENSBTAT00000017430.5
      Conserved Domains (1) summary
      cd07306
      Location:4 → 282
      Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45663910..45690712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024993844.1 → XP_024849612.1  voltage-dependent anion-selective channel protein 1 isoform X2

      UniProtKB/Swiss-Prot
      P45879, Q3ZCK0, Q71SW7
      UniProtKB/TrEMBL
      A0A3Q1MJQ7
      Conserved Domains (1) summary
      cd07306
      Location:4 → 282
      Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

    2. XM_005209336.5 → XP_005209393.1  voltage-dependent anion-selective channel protein 1 isoform X2

      See identical proteins and their annotated locations for XP_005209393.1

      UniProtKB/Swiss-Prot
      P45879, Q3ZCK0, Q71SW7
      UniProtKB/TrEMBL
      A0A3Q1MJQ7
      Conserved Domains (1) summary
      cd07306
      Location:4 → 282
      Porin3_VDAC; Voltage-dependent anion channel of the outer mitochondrial membrane

    3. XM_059887935.1 → XP_059743918.1  voltage-dependent anion-selective channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MJQ7, A0A3Q1MS21
      Related
      ENSBTAP00000072708.2, ENSBTAT00000075754.2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P45879.3 GenPept UniProtKB/Swiss-Prot:P45879

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.