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    Eci1 enoyl-CoA delta isomerase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29740, updated on 2-May-2024

    Summary

    Official Symbol
    Eci1provided by RGD
    Official Full Name
    enoyl-CoA delta isomerase 1provided by RGD
    Primary source
    RGD:61892
    See related
    Ensembl:ENSRNOG00000008843 AllianceGenome:RGD:61892
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dci; MECI
    Summary
    Enables dodecenoyl-CoA delta-isomerase activity and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in mitochondrion. Orthologous to human ECI1 (enoyl-CoA delta isomerase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 1269.9), Kidney (RPKM 940.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eci1 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (13961250..13974595)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13456715..13470061)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (13797573..13810918)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 3 Neighboring gene uncharacterized LOC120095048 Neighboring gene RNA binding protein with serine rich domain 1 Neighboring gene deoxyribonuclease 1 like 2 Neighboring gene E4F transcription factor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fatty acid beta-oxidation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within fatty acid beta-oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fatty acid beta-oxidation TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    enoyl-CoA delta isomerase 1, mitochondrial
    Names
    3,2 trans-enoyl-coenyme A isomerase
    3,2-trans-enoyl-CoA isomerase, mitochondrial
    D3,D2-enoyl-CoA isomerase
    delta(3),Delta(2)-enoyl-CoA isomerase
    dodecenoyl-CoA isomerase
    dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase)
    dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)
    enoyl-Coenzyme A delta isomerase 1
    NP_059002.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017306.4NP_059002.2  enoyl-CoA delta isomerase 1, mitochondrial precursor

      See identical proteins and their annotated locations for NP_059002.2

      Status: PROVISIONAL

      Source sequence(s)
      BC078705
      UniProtKB/Swiss-Prot
      P23965
      UniProtKB/TrEMBL
      A0A8I6AJI3, Q68G41
      Related
      ENSRNOP00000093771.1, ENSRNOT00000119135.1
      Conserved Domains (1) summary
      pfam00378
      Location:39285
      ECH_1; Enoyl-CoA hydratase/isomerase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      13961250..13974595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)