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    Fryl FRY like transcription coactivator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364144, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Frylprovided by RGD
    Official Full Name
    FRY like transcription coactivatorprovided by RGD
    Primary source
    RGD:1311309
    See related
    Ensembl:ENSRNOG00000002248 AllianceGenome:RGD:1311309
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311309
    Summary
    Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be active in cell cortex and site of polarized growth. Orthologous to human FRYL (FRY like transcription coactivator). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 165.9), Heart (RPKM 136.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fryl in Genome Data Viewer
    Location:
    14p11
    Exon count:
    70
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (35307225..35545199)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (34956623..35189738)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (37551109..37757511)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene OCIA domain containing 2 Neighboring gene OCIA domain containing 1 Neighboring gene uncharacterized LOC134481841 Neighboring gene uncharacterized LOC134481842 Neighboring gene solute carrier family 10, member 4 Neighboring gene zygote arrest 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of polarized growth IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein furry homolog-like
    Names
    FRY-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427275.1 → NP_001414204.1  protein furry homolog-like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I5ZTH4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      35307225..35545199
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273429.1 → XP_063129499.1  protein furry homolog-like isoform X13

      UniProtKB/TrEMBL
      A0A8I6A585

    2. XM_063273428.1 → XP_063129498.1  protein furry homolog-like isoform X13

      UniProtKB/TrEMBL
      A0A8I6A585

    3. XM_063273431.1 → XP_063129501.1  protein furry homolog-like isoform X13

      UniProtKB/TrEMBL
      A0A8I6A585

    4. XM_063273430.1 → XP_063129500.1  protein furry homolog-like isoform X13

      UniProtKB/TrEMBL
      A0A8I6A585

    5. XM_063273422.1 → XP_063129492.1  protein furry homolog-like isoform X3

      UniProtKB/TrEMBL
      A0A8I6A585

    6. XM_063273423.1 → XP_063129493.1  protein furry homolog-like isoform X4

      UniProtKB/TrEMBL
      A0A8I6A585

    7. XM_063273420.1 → XP_063129490.1  protein furry homolog-like isoform X1

      UniProtKB/TrEMBL
      A0A8I6A585

    8. XM_063273427.1 → XP_063129497.1  protein furry homolog-like isoform X10

      UniProtKB/TrEMBL
      A0A8I6A585

    9. XM_063273432.1 → XP_063129502.1  protein furry homolog-like isoform X14

      UniProtKB/TrEMBL
      A0A8I5ZTH4

    10. XM_039092707.2 → XP_038948635.1  protein furry homolog-like isoform X7

      UniProtKB/TrEMBL
      A0A8I6A585
      Conserved Domains (3) summary
      pfam14228
      Location:753 → 1925
      MOR2-PAG1_mid; Cell morphogenesis central region
      pfam14222
      Location:168 → 715
      MOR2-PAG1_N; Cell morphogenesis N-terminal
      pfam14225
      Location:2067 → 2320
      MOR2-PAG1_C; Cell morphogenesis C-terminal

    11. XM_039092710.2 → XP_038948638.1  protein furry homolog-like isoform X9

      UniProtKB/TrEMBL
      A0A8I6A585
      Conserved Domains (3) summary
      pfam14228
      Location:753 → 1925
      MOR2-PAG1_mid; Cell morphogenesis central region
      pfam14222
      Location:168 → 715
      MOR2-PAG1_N; Cell morphogenesis N-terminal
      pfam14225
      Location:2067 → 2320
      MOR2-PAG1_C; Cell morphogenesis C-terminal

    12. XM_063273421.1 → XP_063129491.1  protein furry homolog-like isoform X2

      UniProtKB/TrEMBL
      A0A8I6A585

    13. XM_063273424.1 → XP_063129494.1  protein furry homolog-like isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZTH4

    14. XM_006250925.5 → XP_006250987.1  protein furry homolog-like isoform X11

      See identical proteins and their annotated locations for XP_006250987.1

      UniProtKB/TrEMBL
      A0A8I5ZTH4
      Conserved Domains (3) summary
      pfam14222
      Location:168 → 700
      MOR2-PAG1_N; Cell morphogenesis N-terminal
      pfam14225
      Location:2052 → 2305
      MOR2-PAG1_C; Cell morphogenesis C-terminal
      pfam14228
      Location:738 → 1910
      MOR2-PAG1_mid; Cell morphogenesis central region

    15. XM_063273425.1 → XP_063129495.1  protein furry homolog-like isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZTH4

    16. XM_006250926.5 → XP_006250988.1  protein furry homolog-like isoform X12

      See identical proteins and their annotated locations for XP_006250988.1

      UniProtKB/TrEMBL
      A0A8I5ZTH4
      Conserved Domains (3) summary
      pfam14222
      Location:168 → 700
      MOR2-PAG1_N; Cell morphogenesis N-terminal
      pfam14225
      Location:2052 → 2305
      MOR2-PAG1_C; Cell morphogenesis C-terminal
      pfam14228
      Location:738 → 1910
      MOR2-PAG1_mid; Cell morphogenesis central region

    17. XM_063273426.1 → XP_063129496.1  protein furry homolog-like isoform X8

      UniProtKB/TrEMBL
      A0A8I6A585
    Nucleotide Protein Strain
    Heading Accession and Version

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